Details
- scope
- human, postmortem + in vivo neuroimaging, PFC
- claim_text
- Inhibitory signaling between PV basket cells and pyramidal cells is required for gamma oscillatory activity and working memory function in PFC
- section_id
- section_08_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- effect_size
- required for gamma oscillations and working memory
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-08
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- inhibitory GABA signaling in the PFC, especially between parvalbumin positive GABAergic basket cells and excitatory pyramidal cells, is required for gamma oscillatory activity and working memory function
- study_system
- human, postmortem + in vivo neuroimaging, PFC
- section_title
- In Vivo Dynamics and Behavioural Correlates
- evidence_summary
- Convergent in vivo neuroimaging and postmortem evidence that disturbances in PV-pyramidal signaling contribute to altered gamma oscillations and working memory in schizophrenia
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-08
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1016/j.nbd.2018.06.020", "claim": "Inhibitory signaling between PV basket cells and pyramidal cells is required for gamma oscillatory activity and working memory function in PFC", "evidence": "Convergent in vivo neuroimaging and postmortem evidence that disturbances in PV-pyramidal signaling contribute to altered gamma oscillations and working memory in schizophrenia", "effect_size": "required for gamma oscillations and working memory", "text_access": "fulltext", "study_system": "human, postmortem + in vivo neuroimaging, PFC", "replication_status": "independently_replicated", "claim_source_sentence": "inhibitory GABA signaling in the PFC, especially between parvalbumin positive GABAergic basket cells and excitatory pyramidal cells, is required for gamma oscillatory activity and working memory function", "replication_evidence_dois": [ "10.1038/s41386-020-00819-0" ], "effect_size_source_sentence": "disturbances in this signaling contribute to altered gamma oscillations and working memory in schizophrenia" }- source_refs
[ "paper:paper-9d05b8b1560a" ]
- evidence_refs
[ { "ref": "paper:paper-9d05b8b1560a" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }