Version history

{
  "scope": "human, postmortem + in vivo neuroimaging, PFC",
  "claim_text": "Inhibitory signaling between PV basket cells and pyramidal cells is required for gamma oscillatory activity and working memory function in PFC",
  "raw_fields": {
    "n": 0,
    "doi": "10.1016/j.nbd.2018.06.020",
    "claim": "Inhibitory signaling between PV basket cells and pyramidal cells is required for gamma oscillatory activity and working memory function in PFC",
    "evidence": "Convergent in vivo neuroimaging and postmortem evidence that disturbances in PV-pyramidal signaling contribute to altered gamma oscillations and working memory in schizophrenia",
    "effect_size": "required for gamma oscillations and working memory",
    "text_access": "fulltext",
    "study_system": "human, postmortem + in vivo neuroimaging, PFC",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "inhibitory GABA signaling in the PFC, especially between parvalbumin positive GABAergic basket cells and excitatory pyramidal cells, is required for gamma oscillatory activity and working memory function",
    "replication_evidence_dois": [
      "10.1038/s41386-020-00819-0"
    ],
    "effect_size_source_sentence": "disturbances in this signaling contribute to altered gamma oscillations and working memory in schizophrenia"
  },
  "section_id": "section_08_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json",
  "effect_size": "required for gamma oscillations and working memory",
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-08",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-9d05b8b1560a"
  ],
  "source_span": "inhibitory GABA signaling in the PFC, especially between parvalbumin positive GABAergic basket cells and excitatory pyramidal cells, is required for gamma oscillatory activity and working memory function",
  "study_system": "human, postmortem + in vivo neuroimaging, PFC",
  "evidence_refs": [
    {
      "ref": "paper:paper-9d05b8b1560a"
    }
  ],
  "section_title": "In Vivo Dynamics and Behavioural Correlates",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Convergent in vivo neuroimaging and postmortem evidence that disturbances in PV-pyramidal signaling contribute to altered gamma oscillations and working memory in schizophrenia",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-08",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}