Version history

{
  "scope": "mouse V1; in vivo two-photon Ca imaging + in vitro paired recordings of pyramidal and PV interneurons",
  "claim_text": "In mouse V1, in vivo two-photon imaging combined with in vitro intracellular recordings shows pyramidal neurons' co-activation patterns depend strongly on stimulus statistics — inconsistent with strongly biased recurrent connectivity — whereas fast-spiking PV interneurons receive dense uniform input and show stimulus-independent co-activation.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/nn.2876",
    "claim": "In mouse V1, in vivo two-photon imaging combined with in vitro intracellular recordings shows pyramidal neurons' co-activation patterns depend strongly on stimulus statistics — inconsistent with strongly biased recurrent connectivity — whereas fast-spiking PV interneurons receive dense uniform input and show stimulus-independent co-activation.",
    "cite_key": "Hofer2011",
    "evidence": "Two-photon Ca imaging in vivo and intracellular paired recordings in vitro from pyramidal and parvalbumin-expressing fast-spiking interneurons in mouse V1.",
    "effect_size": "Stimulus-dependent pyramidal correlations; near-uniform PV input drive; broadly tuned PV firing",
    "text_access": "abstract_only",
    "study_system": "mouse V1; in vivo two-photon Ca imaging + in vitro paired recordings of pyramidal and PV interneurons",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "In pyramidal cell populations, patterns of neuronal correlations were largely stimulus-dependent, indicating that their responses were not strongly dominated by functionally biased recurrent connectivity.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/nature09880",
      "10.1038/nature14182"
    ],
    "effect_size_source_sentence": "By contrast, visual stimulation only weakly modified co-activation patterns of fast-spiking PV cells, consistent with the observation that these broadly tuned interneurons received very dense and strong synaptic input from nearby p"
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "effect_size": "Stimulus-dependent pyramidal correlations; near-uniform PV input drive; broadly tuned PV firing",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-pm-21765421"
  ],
  "source_span": "In pyramidal cell populations, patterns of neuronal correlations were largely stimulus-dependent, indicating that their responses were not strongly dominated by functionally biased recurrent connectivity.",
  "study_system": "mouse V1; in vivo two-photon Ca imaging + in vitro paired recordings of pyramidal and PV interneurons",
  "evidence_refs": [
    {
      "ref": "paper:paper-pm-21765421"
    }
  ],
  "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon Ca imaging in vivo and intracellular paired recordings in vitro from pyramidal and parvalbumin-expressing fast-spiking interneurons in mouse V1.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}