In mouse V1, in vivo two-photon imaging combined with in vitro intracellular re…

In mouse V1, in vivo two-photon imaging combined with in vitro intracellular recordings shows pyramidal neurons' co-activation patterns depend strongly on stimulus statistics — inconsistent with strongly biased recurrent connectivity — whereas fast-spiking PV interneurons receive dense uniform input and show stimulus-independent co-activation.

{
  "n": 0,
  "doi": "10.1038/nn.2876",
  "claim": "In mouse V1, in vivo two-photon imaging combined with in vitro intracellular recordings shows pyramidal neurons' co-activation patterns depend strongly on stimulus statistics — inconsistent with strongly biased recurrent connectivity — whereas fast-spiking PV interneurons receive dense uniform input and show stimulus-independent co-activation.",
  "cite_key": "Hofer2011",
  "evidence": "Two-photon Ca imaging in vivo and intracellular paired recordings in vitro from pyramidal and parvalbumin-expressing fast-spiking interneurons in mouse V1.",
  "effect_size": "Stimulus-dependent pyramidal correlations; near-uniform PV input drive; broadly tuned PV firing",
  "text_access": "abstract_only",
  "study_system": "mouse V1; in vivo two-photon Ca imaging + in vitro paired recordings of pyramidal and PV interneurons",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "In pyramidal cell populations, patterns of neuronal correlations were largely stimulus-dependent, indicating that their responses were not strongly dominated by functionally biased recurrent connectivity.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/nature09880",
    "10.1038/nature14182"
  ],
  "effect_size_source_sentence": "By contrast, visual stimulation only weakly modified co-activation patterns of fast-spiking PV cells, consistent with the observation that these broadly tuned interneurons received very dense and strong synaptic input from nearby p"
}

[
  "paper:paper-pm-21765421"
]

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  }
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    "Local review repositories are read-only inputs.",
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