- claim_text
Local connectivity comparison between mouse and human cortex reveals that excitatory-to-excitatory synaptic dynamics in human cortex differ from those in mouse cortex and vary with depth across L2 and L3, indicating that mouse translaminar synaptic rules cannot be assumed to generalize across species.
- raw_fields
{
"n": 0,
"doi": "10.1126/science.abj5861",
"claim": "Local connectivity comparison between mouse and human cortex reveals that excitatory-to-excitatory synaptic dynamics in human cortex differ from those in mouse cortex and vary with depth across L2 and L3, indicating that mouse translaminar synaptic rules cannot be assumed to generalize across species.",
"cite_key": "Campagnola2022",
"evidence": "Allen Institute synaptic physiology dataset, mouse vs human cortex multi-patch.",
"effect_size": "Species-level divergence in E→E dynamics in L2/3.",
"text_access": "abstract_only",
"study_system": "mouse and human neocortex multi-patch dataset",
"argument_role": "supporting",
"replication_status": "single_study_landmark",
"claim_source_sentence": "In the human cortex, excitatory-to-excitatory synaptic dynamics are distinct from those in the mouse cortex and vary with depth across layers 2 and 3.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": "In the human cortex, excitatory-to-excitatory synaptic dynamics are distinct from those in the mouse cortex and vary with depth across layers 2 and 3."
}- source_refs
[
"paper:paper-pm-40128391"
]
- evidence_refs
[
{
"ref": "paper:paper-pm-40128391"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}