Translaminar excitatory loops in mouse: L4→L2/3→L5→L6→L4 within the column; asy…

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Translaminar excitatory loops in mouse: L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections

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  • 1Citationpaper:paper-bdc020492b80Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1 Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3 Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 The benchmark for the within-column matrix is the C2 barrel column dataset of 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 The benchmark for the within-column matrix is the C2 barrel column dataset of 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 The benchmark for the within-column matrix is the C2 barrel column dataset of 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 The benchmark for the within-column matrix is the C2 barrel column dataset of 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 The benchmark for the within-column matrix is the C2 barrel column dataset of 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 The benchmark for the within-column matrix is the C2 barrel column dataset of 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 The benchmark for the within-column matrix is the C2 barrel column dataset of 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 The benchmark for the within-column matrix is the C2 barrel column dataset of 3Citationpaper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9, where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column’s strongest excitatory drive. Subsequent pa...

  • 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 4Citationpaper:paper-e4f11964cdc5Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 5Citationpaper:paper-14e5fb681943Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by 6Citationpaper:paper-20192df165b8Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9, who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...

  • 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1. A subsequent 2P optomapping study sampled 30,...

  • 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3. A subsequent 2P optomapping study sampled 30,...

  • 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5. A subsequent 2P optomapping study sampled 30,...

  • 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7. A subsequent 2P optomapping study sampled 30,...

  • 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources 7Citationpaper:paper-7ac22819c082Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9. A subsequent 2P optomapping study sampled 30,...

  • 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1. A subsequent 2P optomapping study sampled 30,...

  • 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 Cross-study coverage of translaminar E→E pathways in mouse cortex. Categorical encoding of five canonical translaminar pathways (L4→L2/3, L2/3→L5, L5-IT→L2/3, L4→L5, L6→L4) across paired-recording 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3, glutamate-uncaging 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4, two-photon optogenetic 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5, 2P optomapping 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 and EM connectomic 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7 datasets spanning mouse S1, vM1, vS1, S2 and V1 + HVAs. Panel a classifies ea...

  • 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 Cross-study coverage of translaminar E→E pathways in mouse cortex. Categorical encoding of five canonical translaminar pathways (L4→L2/3, L2/3→L5, L5-IT→L2/3, L4→L5, L6→L4) across paired-recording 8Citationpaper:paper-aecac0566e4aPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9, glutamate-uncaging 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0, two-photon optogenetic 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1, 2P optomapping 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2 and EM connectomic 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3 datasets spanning mouse S1, vM1, vS1, S2 and V1 + HVAs. Panel a classifies ea...

  • 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 Cross-study coverage of translaminar E→E pathways in mouse cortex. Categorical encoding of five canonical translaminar pathways (L4→L2/3, L2/3→L5, L5-IT→L2/3, L4→L5, L6→L4) across paired-recording 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5, glutamate-uncaging 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6, two-photon optogenetic 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7, 2P optomapping 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8 and EM connectomic 9Citationpaper:paper-88749d37d387Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9 datasets spanning mouse S1, vM1, vS1, S2 and V1 + HVAs. Panel a classifies ea...

  • 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference0 Cross-study coverage of translaminar E→E pathways in mouse cortex. Categorical encoding of five canonical translaminar pathways (L4→L2/3, L2/3→L5, L5-IT→L2/3, L4→L5, L6→L4) across paired-recording 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference1, glutamate-uncaging 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference2, two-photon optogenetic 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference3, 2P optomapping 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference4 and EM connectomic 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference5 datasets spanning mouse S1, vM1, vS1, S2 and V1 + HVAs. Panel a classifies ea...

  • 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference6 Cross-study coverage of translaminar E→E pathways in mouse cortex. Categorical encoding of five canonical translaminar pathways (L4→L2/3, L2/3→L5, L5-IT→L2/3, L4→L5, L6→L4) across paired-recording 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference7, glutamate-uncaging 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference8, two-photon optogenetic 10Citationpaper:126d45d1-af34-4bb8-acea-67031f7d19a6Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference9, 2P optomapping 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference00 and EM connectomic 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference01 datasets spanning mouse S1, vM1, vS1, S2 and V1 + HVAs. Panel a classifies ea...

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference02 Quantitative weight of L5-IT→L2/3 vs L4→L2/3 into L2/3 pyramidal cells. 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference03 observe strong excitatory input from L5 intratelencephalic neurons onto V1 L2/3 pyramidal cells alongside the canonical L4 source, while the original C2 barrel-column paired-recording matrix 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference04 reports L4 as the column’s strongest excitatory presynaptic source and does not separately quantify a strong L5-IT contribution....

  • 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference05 Quantitative weight of L5-IT→L2/3 vs L4→L2/3 into L2/3 pyramidal cells. 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference06 observe strong excitatory input from L5 intratelencephalic neurons onto V1 L2/3 pyramidal cells alongside the canonical L4 source, while the original C2 barrel-column paired-recording matrix 2Citationpaper:82e14b69-8c1b-41b8-b15b-f103a44caf3fPairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}sec-paired-recording, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...content/04_translaminar.md:line 4Open reference07 reports L4 as the column’s strongest excitatory presynaptic source and does not separately quantify a strong L5-IT contribution....

  • ... 232 additional anchors in refs_json

References

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  2. [Hooks2011] paper:82e14b69-8c1b-41b8-b15b-f103a44caf3f “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  3. [Hooks2013] paper:fc06108f-75bb-4dd7-9d5e-3b006f8c4156 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  4. [Anderson2010] paper:paper-e4f11964cdc5 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  5. [Hage2022] paper:paper-14e5fb681943 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  6. [Chou2025] paper:paper-20192df165b8 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  7. [Ding2025] paper:paper-7ac22819c082 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  8. [TheMICrONSConsortium2025] paper:paper-aecac0566e4a “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  9. [Weiler2008] paper:paper-88749d37d387 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  10. [Bureau2006] paper:126d45d1-af34-4bb8-acea-67031f7d19a6 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  11. [Petreanu2007] paper:987379eb-ecdd-42eb-818f-383280a8fca9 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  12. [Petreanu2009] paper:914d374f-2785-4b45-b1ed-71edc0641508 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  13. [Adesnik2010] paper:paper-c5d8aa75fd02 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  14. [Olsen2012] paper:paper-4a4c871adcb0 “Pairwise excitatory connection probabilities and unitary EPSPs, the unit measurements catalogued in {ref}`sec-paired-recording`, only become a description of cortical architecture when they are assembled into the inter-layer loops they imply. The most-cited assembly is the textbook canonical microcircuit — thalamic input arrives in L4, ascends into L2/3, descends into L5, and closes through L6 back onto L4 — and in...”
  15. [Cossell2015] paper:paper-c4ad527c9bfb “The benchmark for the within-column matrix is the C2 barrel column dataset of [Lefort2009], where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column's strongest excitatory drive. Subsequent pa...”
  16. [Ko2011] paper:paper-31c9e0b4d258 “The benchmark for the within-column matrix is the C2 barrel column dataset of [Lefort2009], where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column's strongest excitatory drive. Subsequent pa...”
  17. [Meyer2018] paper:paper-068169bdf0b1 “The benchmark for the within-column matrix is the C2 barrel column dataset of [Lefort2009], where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column's strongest excitatory drive. Subsequent pa...”
  18. [Jouhanneau2015] paper:paper-6d3d01cb91a6 “The benchmark for the within-column matrix is the C2 barrel column dataset of [Lefort2009], where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column's strongest excitatory drive. Subsequent pa...”
  19. [Jouhanneau2019] paper:paper-47adc87cd10d “The benchmark for the within-column matrix is the C2 barrel column dataset of [Lefort2009], where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column's strongest excitatory drive. Subsequent pa...”
  20. [Campagnola2022] paper:paper-pm-40128391 “The benchmark for the within-column matrix is the C2 barrel column dataset of [Lefort2009], where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column's strongest excitatory drive. Subsequent pa...”
  21. [Joshi2015] paper:paper-1434a55a9a22 “The benchmark for the within-column matrix is the C2 barrel column dataset of [Lefort2009], where multiple simultaneous whole-cell recordings sampled connections systematically across all six layers and reported that connection probability and EPSP amplitude depend strongly on the laminar position of both pre- and postsynaptic cell, with presynaptic L4 providing the column's strongest excitatory drive. Subsequent pa...”
  22. [Katzel2011] paper:paper-2d91d6473ba4 “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  23. [Kiritani2012] paper:paper-e1291622a820 “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  24. [Suter2015] paper:paper-b11b84d85abf “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  25. [Yamawaki2021] paper:paper-15b98c6c015d “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  26. [Yamawaki2014] paper:paper-a29242ac688f “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  27. [Bortone2014] paper:paper-124c2564d88b “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  28. [VelezFort2014] paper:paper-fba788abe5dd “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  29. [Frandolig2019] paper:paper-ab9407c26ea7 “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  30. [Crandall2017] paper:paper-78f81bfb11b4 “Whether the same matrix repeats across cortical areas was first answered systematically in vibrissal M1, vibrissal S1 and S2 by [Hooks2011], who used laser-scanning photostimulation to map laminar input fields onto pyramidal neurons in each area and reported that the L2/3→L5 descending pathway was the most conserved feature across the three areas while L4→L2/3 and L6-related pathways were the most variable, a cross-...”
  31. [VargasOrtiz2025] paper:paper-113803f405c0 “V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources [Hage2022]. A subsequent 2P optomapping study sampled 30,...”
  32. [Meng2020] paper:paper-b5c8ab0ad4f0 “V1 has been the principal arena for re-measuring the translaminar matrix with techniques that scale beyond the multi-patch limit. Two-photon holographic stimulation paired with whole-cell recording reports a heterogeneous excitatory input pattern onto L2/3 pyramidal cells in which L4 excitatory neurons and intralaminar interneurons are the most common sources [Hage2022]. A subsequent 2P optomapping study sampled 30,...”

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