Version history

{
  "scope": "adult mouse V1 (slice); multipatch electrophysiology with two-photon optogenetic supplementation",
  "claim_text": "Multipatch and 2-photon optogenetic characterization of mouse V1 finds connections between excitatory cell classes and layers are sparse but present, with most mouse pyramidal–pyramidal synapses showing short-term depression and a L2/3 subset displaying facilitation.",
  "raw_fields": {
    "n": 0,
    "doi": "10.7554/elife.37349",
    "claim": "Multipatch and 2-photon optogenetic characterization of mouse V1 finds connections between excitatory cell classes and layers are sparse but present, with most mouse pyramidal–pyramidal synapses showing short-term depression and a L2/3 subset displaying facilitation.",
    "cite_key": "Seeman2018",
    "evidence": "Multipatch electrophysiology supplemented with two-photon optogenetics in adult mouse V1 slices; intralaminar excitatory–excitatory connectivity and short-term plasticity quantified.",
    "effect_size": "Sparse but uniform intralaminar E→E connectivity across layers; majority depressing, L2/3 subset facilitating",
    "text_access": "abstract_only",
    "study_system": "adult mouse V1 (slice); multipatch electrophysiology with two-photon optogenetic supplementation",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "We find that connections are sparse but present among all excitatory cell classes and layers we sampled, and that most mouse synapses exhibited short-term depression with similar dynamics.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1016/j.xinn.2024.100735",
      "10.7554/eLife.71103"
    ],
    "effect_size_source_sentence": "Synaptic signaling between a subset of layer 2/3 neurons, however, exhibited facilitation."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "effect_size": "Sparse but uniform intralaminar E→E connectivity across layers; majority depressing, L2/3 subset facilitating",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-pm-30256194"
  ],
  "source_span": "We find that connections are sparse but present among all excitatory cell classes and layers we sampled, and that most mouse synapses exhibited short-term depression with similar dynamics.",
  "study_system": "adult mouse V1 (slice); multipatch electrophysiology with two-photon optogenetic supplementation",
  "evidence_refs": [
    {
      "ref": "paper:paper-pm-30256194"
    }
  ],
  "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Multipatch electrophysiology supplemented with two-photon optogenetics in adult mouse V1 slices; intralaminar excitatory–excitatory connectivity and short-term plasticity quantified.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}