Version history

{
  "scope": "mouse LP and dLGN axonal projections to V1 (two-photon imaging)",
  "claim_text": "The mouse pulvinar homologue (LP) provides V1 with diverse contextual signals (visual, motor, visuomotor mismatch), whereas dLGN delivers retinotopically precise sensory signals.",
  "raw_fields": {
    "n": 1825,
    "doi": "10.1038/nn.4197",
    "claim": "The mouse pulvinar homologue (LP) provides V1 with diverse contextual signals (visual, motor, visuomotor mismatch), whereas dLGN delivers retinotopically precise sensory signals.",
    "cite_key": "Roth2015",
    "evidence": "In vivo two-photon calcium imaging of LP and dLGN axonal boutons in mouse V1 during locomotion and visual flow manipulation.",
    "effect_size": "dLGN n=2317 RFs (7 mice); LP n=1825 RFs (13 mice); V1 n=356 RFs (4 mice). LP visuomotor mismatch activity 30±7%, dLGN 6±8%.",
    "text_access": "fulltext",
    "study_system": "mouse LP and dLGN axonal projections to V1 (two-photon imaging)",
    "source_cluster_id": "cluster_05",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "We found that dLGN conveys retinotopically precise visual signals, while LP provides distributed information from the visual scene.",
    "replication_evidence_dois": [
      "10.1038/nn.4197",
      "10.1126/science.1223082"
    ],
    "effect_size_source_sentence": "Interestingly, LP boutons on the whole were more active in response to an onset of visuomotor divergence than during a period of varying but sustained visuomotor discrepancies (mean difference in activity, LP: 30 ± 7%; P = 10 −4 , Wilcoxon signed-rank test)."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "effect_size": "dLGN n=2317 RFs (7 mice); LP n=1825 RFs (13 mice); V1 n=356 RFs (4 mice). LP visuomotor mismatch activity 30±7%, dLGN 6±8%.",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-06",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-b92f6eb9a796"
  ],
  "source_span": "We found that dLGN conveys retinotopically precise visual signals, while LP provides distributed information from the visual scene.",
  "study_system": "mouse LP and dLGN axonal projections to V1 (two-photon imaging)",
  "evidence_refs": [
    {
      "ref": "paper:paper-b92f6eb9a796"
    }
  ],
  "section_title": "Thalamic Feedback: Closing the Loop",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "In vivo two-photon calcium imaging of LP and dLGN axonal boutons in mouse V1 during locomotion and visual flow manipulation.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-06",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}