Details

scope
mouse LP and dLGN axonal projections to V1 (two-photon imaging)
claim_text
The mouse pulvinar homologue (LP) provides V1 with diverse contextual signals (visual, motor, visuomotor mismatch), whereas dLGN delivers retinotopically precise sensory signals.
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
effect_size
dLGN n=2317 RFs (7 mice); LP n=1825 RFs (13 mice); V1 n=356 RFs (4 mice). LP visuomotor mismatch activity 30±7%, dLGN 6±8%.
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-06
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
We found that dLGN conveys retinotopically precise visual signals, while LP provides distributed information from the visual scene.
study_system
mouse LP and dLGN axonal projections to V1 (two-photon imaging)
section_title
Thalamic Feedback: Closing the Loop
evidence_summary
In vivo two-photon calcium imaging of LP and dLGN axonal boutons in mouse V1 during locomotion and visual flow manipulation.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-06
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 1825,
  "doi": "10.1038/nn.4197",
  "claim": "The mouse pulvinar homologue (LP) provides V1 with diverse contextual signals (visual, motor, visuomotor mismatch), whereas dLGN delivers retinotopically precise sensory signals.",
  "cite_key": "Roth2015",
  "evidence": "In vivo two-photon calcium imaging of LP and dLGN axonal boutons in mouse V1 during locomotion and visual flow manipulation.",
  "effect_size": "dLGN n=2317 RFs (7 mice); LP n=1825 RFs (13 mice); V1 n=356 RFs (4 mice). LP visuomotor mismatch activity 30±7%, dLGN 6±8%.",
  "text_access": "fulltext",
  "study_system": "mouse LP and dLGN axonal projections to V1 (two-photon imaging)",
  "source_cluster_id": "cluster_05",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "We found that dLGN conveys retinotopically precise visual signals, while LP provides distributed information from the visual scene.",
  "replication_evidence_dois": [
    "10.1038/nn.4197",
    "10.1126/science.1223082"
  ],
  "effect_size_source_sentence": "Interestingly, LP boutons on the whole were more active in response to an onset of visuomotor divergence than during a period of varying but sustained visuomotor discrepancies (mean difference in activity, LP: 30 ± 7%; P = 10 −4 , Wilcoxon signed-rank test)."
}
source_refs
[
  "paper:paper-b92f6eb9a796"
]
evidence_refs
[
  {
    "ref": "paper:paper-b92f6eb9a796"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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