- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2018.02.029",
"claim": "Nav1.1-overexpressing interneuron transplants enhance gamma oscillations and improve cognition in AD model mice, while Nav1.1-deficient transplants cause behavioral abnormalities in wild-type mice.",
"evidence": "",
"effect_size": "enhanced gamma oscillatory activity; improved cognitive functions",
"text_access": "abstract_only",
"study_system": "hAPP-transgenic mouse model of AD",
"replication_status": "replication_unknown",
"claim_source_sentence": "Nav1.1-overexpressing, but not wild-type, interneuron transplants derived from the embryonic medial ganglionic eminence enhance behavior-dependent gamma oscillatory activity, reduce network hypersynchrony, and improve cognitive functions in hAPP-transgenic mice.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "Nav1.1-overexpressing, but not wild-type, interneuron transplants derived from the embryonic medial ganglionic eminence enhance behavior-dependent gamma oscillatory activity, reduce network hypersynchrony, and improve cognitive functions in hAPP-transgenic mice"
}- source_refs
[
"paper:paper-97c54b332720"
]
- source_span
Nav1.1-overexpressing, but not wild-type, interneuron transplants derived from the embryonic medial ganglionic eminence enhance behavior-dependent gamma oscillatory activity, reduce network hypersynchrony, and improve cognitive functions in hAPP-transgenic mice.
- evidence_refs
[
{
"ref": "paper:paper-97c54b332720"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}