Version history

{
  "scope": "Acute slices of mouse M1, S1 and V1; ChR2 in GABAergic neurons; laser scanning photostimulation to excitatory cells across all principal layers",
  "claim_text": "In mouse M1, S1 and V1, subsets of L2/3 and L5B pyramidal cells receive substantial translaminar inputs that span beyond the home layer, with the proportion of translaminar-receiving cells highest in V1, intermediate in S1 and absent in M1.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/nn.2687",
    "claim": "In mouse M1, S1 and V1, subsets of L2/3 and L5B pyramidal cells receive substantial translaminar inputs that span beyond the home layer, with the proportion of translaminar-receiving cells highest in V1, intermediate in S1 and absent in M1.",
    "cite_key": "Katzel2011",
    "evidence": "Genetically targeted photostimulation of GABAergic neurons in a ChR2 knock-in mouse line to map laminar input patterns across M1, S1 and V1.",
    "effect_size": "Translaminar-input-receiving pyramids: prominent V1 > S1 > M1 (0).",
    "text_access": "abstract_only",
    "study_system": "Acute slices of mouse M1, S1 and V1; ChR2 in GABAergic neurons; laser scanning photostimulation to excitatory cells across all principal layers",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "Subsets of pyramidal cells in layers 2/3 and 5B received extensive translaminar inhibition. These neurons were prominent in V1, where they might correspond to complex cells, less numerous in barrel cortex and absent in M1.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Subsets of pyramidal cells in layers 2/3 and 5B received extensive translaminar inhibition."
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Translaminar-input-receiving pyramids: prominent V1 > S1 > M1 (0).",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-2d91d6473ba4"
  ],
  "source_span": "Subsets of pyramidal cells in layers 2/3 and 5B received extensive translaminar inhibition. These neurons were prominent in V1, where they might correspond to complex cells, less numerous in barrel cortex and absent in M1.",
  "study_system": "Acute slices of mouse M1, S1 and V1; ChR2 in GABAergic neurons; laser scanning photostimulation to excitatory cells across all principal layers",
  "evidence_refs": [
    {
      "ref": "paper:paper-2d91d6473ba4"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Genetically targeted photostimulation of GABAergic neurons in a ChR2 knock-in mouse line to map laminar input patterns across M1, S1 and V1.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}