Details
- scope
- Acute slices of mouse M1, S1 and V1; ChR2 in GABAergic neurons; laser scanning photostimulation to excitatory cells across all principal layers
- claim_text
- In mouse M1, S1 and V1, subsets of L2/3 and L5B pyramidal cells receive substantial translaminar inputs that span beyond the home layer, with the proportion of translaminar-receiving cells highest in V1, intermediate in S1 and absent in M1.
- section_id
- section_04
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- effect_size
- Translaminar-input-receiving pyramids: prominent V1 > S1 > M1 (0).
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- source_kind
- review_finding
- source_path
- evidence/section_04_evidence_package.json
- source_span
- Subsets of pyramidal cells in layers 2/3 and 5B received extensive translaminar inhibition. These neurons were prominent in V1, where they might correspond to complex cells, less numerous in barrel cortex and absent in M1.
- study_system
- Acute slices of mouse M1, S1 and V1; ChR2 in GABAergic neurons; laser scanning photostimulation to excitatory cells across all principal layers
- section_title
- 4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
- evidence_summary
- Genetically targeted photostimulation of GABAergic neurons in a ChR2 knock-in mouse line to map laminar input patterns across M1, S1 and V1.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- single_study
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1038/nn.2687", "claim": "In mouse M1, S1 and V1, subsets of L2/3 and L5B pyramidal cells receive substantial translaminar inputs that span beyond the home layer, with the proportion of translaminar-receiving cells highest in V1, intermediate in S1 and absent in M1.", "cite_key": "Katzel2011", "evidence": "Genetically targeted photostimulation of GABAergic neurons in a ChR2 knock-in mouse line to map laminar input patterns across M1, S1 and V1.", "effect_size": "Translaminar-input-receiving pyramids: prominent V1 > S1 > M1 (0).", "text_access": "abstract_only", "study_system": "Acute slices of mouse M1, S1 and V1; ChR2 in GABAergic neurons; laser scanning photostimulation to excitatory cells across all principal layers", "argument_role": "supporting", "replication_status": "single_study", "claim_source_sentence": "Subsets of pyramidal cells in layers 2/3 and 5B received extensive translaminar inhibition. These neurons were prominent in V1, where they might correspond to complex cells, less numerous in barrel cortex and absent in M1.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Subsets of pyramidal cells in layers 2/3 and 5B received extensive translaminar inhibition." }- source_refs
[ "paper:paper-2d91d6473ba4" ]
- evidence_refs
[ { "ref": "paper:paper-2d91d6473ba4" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }