Details
- scope
- PD STN-DBS patients with sensing implants (9 subjects, 15 STNs)
- claim_text
- 60 Hz STN-DBS improves bradykinesia despite amplifying alpha/low-beta (11-15 Hz) power, decoupling motor benefit from beta-band attenuation.
- section_id
- section_14
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
- effect_size
- Alpha/low-beta amplification at 60 Hz P = 0.007
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-14
- source_kind
- review_finding
- source_path
- evidence/section_14_evidence_package.json
- source_span
- In fact, 60-Hz DBS amplified alpha/low-beta (11-15 Hz, P = 0.007) and attenuated high-beta power (19-27 Hz, P < 0.001), whereas 140-Hz DBS broadly attenuated beta power (15-30 Hz, P < 0.001).
- study_system
- PD STN-DBS patients with sensing implants (9 subjects, 15 STNs)
- section_title
- Loop Dysfunction in Neurological and Psychiatric Disease
- evidence_summary
- Sensing-neurostimulator (Activa PC+S) recordings of STN LFP during 60 Hz, 140 Hz, and 20 Hz DBS in freely moving PD subjects performing wrist movements.
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-14
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": 9, "doi": "10.1002/mds.26837", "claim": "60 Hz STN-DBS improves bradykinesia despite amplifying alpha/low-beta (11-15 Hz) power, decoupling motor benefit from beta-band attenuation.", "cite_key": "Blumenfeld2016", "evidence": "Sensing-neurostimulator (Activa PC+S) recordings of STN LFP during 60 Hz, 140 Hz, and 20 Hz DBS in freely moving PD subjects performing wrist movements.", "effect_size": "Alpha/low-beta amplification at 60 Hz P = 0.007", "text_access": "abstract_only", "study_system": "PD STN-DBS patients with sensing implants (9 subjects, 15 STNs)", "source_cluster_id": "cluster_13", "replication_status": "independently_replicated", "claim_source_sentence": "In fact, 60-Hz DBS amplified alpha/low-beta (11-15 Hz, P = 0.007) and attenuated high-beta power (19-27 Hz, P < 0.001), whereas 140-Hz DBS broadly attenuated beta power (15-30 Hz, P < 0.001).", "replication_evidence_dois": [ "10.1186/s41016-025-00415-5", "10.1186/s43556-026-00445-0" ], "effect_size_source_sentence": "In fact, 60-Hz DBS amplified alpha/low-beta (11-15 Hz, P = 0.007) and attenuated high-beta power (19-27 Hz, P < 0.001), whereas 140-Hz DBS broadly attenuated beta power (15-30 Hz, P < 0.001)." }- source_refs
[ "paper:paper-82ec0c706c35" ]
- evidence_refs
[ { "ref": "paper:paper-82ec0c706c35" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }