Version history

{
  "scope": "PD STN-DBS patients with sensing implants (9 subjects, 15 STNs)",
  "claim_text": "60 Hz STN-DBS improves bradykinesia despite amplifying alpha/low-beta (11-15 Hz) power, decoupling motor benefit from beta-band attenuation.",
  "raw_fields": {
    "n": 9,
    "doi": "10.1002/mds.26837",
    "claim": "60 Hz STN-DBS improves bradykinesia despite amplifying alpha/low-beta (11-15 Hz) power, decoupling motor benefit from beta-band attenuation.",
    "cite_key": "Blumenfeld2016",
    "evidence": "Sensing-neurostimulator (Activa PC+S) recordings of STN LFP during 60 Hz, 140 Hz, and 20 Hz DBS in freely moving PD subjects performing wrist movements.",
    "effect_size": "Alpha/low-beta amplification at 60 Hz P = 0.007",
    "text_access": "abstract_only",
    "study_system": "PD STN-DBS patients with sensing implants (9 subjects, 15 STNs)",
    "source_cluster_id": "cluster_13",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "In fact, 60-Hz DBS amplified alpha/low-beta (11-15 Hz, P = 0.007) and attenuated high-beta power (19-27 Hz, P < 0.001), whereas 140-Hz DBS broadly attenuated beta power (15-30 Hz, P < 0.001).",
    "replication_evidence_dois": [
      "10.1186/s41016-025-00415-5",
      "10.1186/s43556-026-00445-0"
    ],
    "effect_size_source_sentence": "In fact, 60-Hz DBS amplified alpha/low-beta (11-15 Hz, P = 0.007) and attenuated high-beta power (19-27 Hz, P < 0.001), whereas 140-Hz DBS broadly attenuated beta power (15-30 Hz, P < 0.001)."
  },
  "section_id": "section_14",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "effect_size": "Alpha/low-beta amplification at 60 Hz P = 0.007",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-14",
  "source_kind": "review_finding",
  "source_path": "evidence/section_14_evidence_package.json",
  "source_refs": [
    "paper:paper-82ec0c706c35"
  ],
  "source_span": "In fact, 60-Hz DBS amplified alpha/low-beta (11-15 Hz, P = 0.007) and attenuated high-beta power (19-27 Hz, P < 0.001), whereas 140-Hz DBS broadly attenuated beta power (15-30 Hz, P < 0.001).",
  "study_system": "PD STN-DBS patients with sensing implants (9 subjects, 15 STNs)",
  "evidence_refs": [
    {
      "ref": "paper:paper-82ec0c706c35"
    }
  ],
  "section_title": "Loop Dysfunction in Neurological and Psychiatric Disease",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Sensing-neurostimulator (Activa PC+S) recordings of STN LFP during 60 Hz, 140 Hz, and 20 Hz DBS in freely moving PD subjects performing wrist movements.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-14",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}