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- Live5/17/2026, 4:35:28 PM
b6f5ec43d3c4Content snapshot
{ "scope": "mouse posterior parietal cortex (PPC); two-photon calcium imaging during virtual-navigation decision task", "claim_text": "During working-memory decisions in a virtual navigation task, mouse posterior parietal cortex neurons fire as choice-specific sequences spanning the trial — not as long-lived stable persistent states — and cells participating in distinct sequences are anatomically intermingled at sub-100-micrometre scales.", "raw_fields": { "n": 0, "doi": "10.1038/nature10918", "claim": "During working-memory decisions in a virtual navigation task, mouse posterior parietal cortex neurons fire as choice-specific sequences spanning the trial — not as long-lived stable persistent states — and cells participating in distinct sequences are anatomically intermingled at sub-100-micrometre scales.", "cite_key": "Harvey2012", "evidence": "Sequence-based, not stable-attractor, dynamics described in PPC; the same dataset framing has been extended in subsequent PPC imaging studies.", "effect_size": "", "text_access": "abstract_only", "study_system": "mouse posterior parietal cortex (PPC); two-photon calcium imaging during virtual-navigation decision task", "argument_role": "supporting", "replication_status": "independently_replicated", "claim_source_sentence": "Distinct sequences of neurons were triggered on trials with opposite behavioural choices and defined divergent, choice-specific trajectories through a state space of neuronal population activity.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.1038/nn.4403" ], "effect_size_source_sentence": "Cells participating in the different sequences and at distinct time points in the task were anatomically intermixed over microcircuit length scales (<100 micrometres)." }, "section_id": "section_10", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json", "effect_size": "", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-10-persistent-activity", "source_kind": "review_finding", "source_path": "evidence/section_10_evidence_package.json", "source_refs": [ "paper:paper-8bd2d21e65e2" ], "source_span": "Distinct sequences of neurons were triggered on trials with opposite behavioural choices and defined divergent, choice-specific trajectories through a state space of neuronal population activity.", "study_system": "mouse posterior parietal cortex (PPC); two-photon calcium imaging during virtual-navigation decision task", "evidence_refs": [ { "ref": "paper:paper-8bd2d21e65e2" } ], "section_title": "10. Physiological signature II — persistent activity and attractor dynamics supported by E→E recurrence (delay-period activity in mouse PFC/ALM, working memory, head-direction)", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Sequence-based, not stable-attractor, dynamics described in PPC; the same dataset framing has been extended in subsequent PPC imaging studies.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "independently_replicated", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-10-persistent-activity", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }