Details
- scope
- Mouse S1; dual retrograde tracing (L1 + local L5); per-layer quantification of double-labelled neurons
- section_id
- section_04
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- effect_size
- Double-labelled fraction: L2/3 = 45%, L5a = 33%, L5b = 20%.
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- source_kind
- review_finding
- source_path
- evidence/section_04_evidence_package.json
- source_span
- These analyses showed that 45% of all neurons in L2/3, 33% of all neurons in L5a, and 20% of all neurons in L5b were double labeled.
- study_system
- Mouse S1; dual retrograde tracing (L1 + local L5); per-layer quantification of double-labelled neurons
- section_title
- 4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
- evidence_summary
- Dual retrograde tracing from L1 and from local L5 pyramidal neurons in mouse S1; quantification of double-labelled cells per layer.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- single_study
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- claim_text
In mouse S1, double-retrograde tracing reveals substantial cross-targeting: 45% of L2/3 neurons, 33% of L5a neurons and 20% of L5b neurons both contact L1 and are presynaptic to local L5 pyramidal cells, implying that L1-targeting inputs and L5-targeting inputs are largely sourced from the same intracortical neuron pools.
- raw_fields
{ "n": 0, "doi": "10.1093/cercor/bhad371", "claim": "In mouse S1, double-retrograde tracing reveals substantial cross-targeting: 45% of L2/3 neurons, 33% of L5a neurons and 20% of L5b neurons both contact L1 and are presynaptic to local L5 pyramidal cells, implying that L1-targeting inputs and L5-targeting inputs are largely sourced from the same intracortical neuron pools.", "cite_key": "Ledderose2023", "evidence": "Dual retrograde tracing from L1 and from local L5 pyramidal neurons in mouse S1; quantification of double-labelled cells per layer.", "effect_size": "Double-labelled fraction: L2/3 = 45%, L5a = 33%, L5b = 20%.", "text_access": "fulltext", "study_system": "Mouse S1; dual retrograde tracing (L1 + local L5); per-layer quantification of double-labelled neurons", "argument_role": "supporting", "replication_status": "single_study", "claim_source_sentence": "These analyses showed that 45% of all neurons in L2/3, 33% of all neurons in L5a, and 20% of all neurons in L5b were double labeled.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "These analyses showed that 45% of all neurons in L2/3, 33% of all neurons in L5a, and 20% of all neurons in L5b were double labeled." }- source_refs
[ "paper:paper-189d92c83cf0" ]
- evidence_refs
[ { "ref": "paper:paper-189d92c83cf0" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }