Version history

{
  "scope": "mouse cortico-basal ganglia loops; rabies virus retrograde transsynaptic tracing",
  "claim_text": "Limbic-to-motor 'open loop' connections coexist with classical closed loops: ventral and dorsomedial striatum can send signals back to motor cortex without receiving direct inputs from it.",
  "raw_fields": {
    "n": 0,
    "doi": "10.7554/elife.49995",
    "claim": "Limbic-to-motor 'open loop' connections coexist with classical closed loops: ventral and dorsomedial striatum can send signals back to motor cortex without receiving direct inputs from it.",
    "cite_key": "Aoki2019",
    "evidence": "Rabies virus tracing in mice showed neurons in ventral, dorsomedial, and tail striatum project transsynaptically to M1/M2 without receiving M1/M2 direct inputs, confirming open-loop architecture in parallel with the canonical closed motor loop.",
    "effect_size": "",
    "text_access": "fulltext",
    "study_system": "mouse cortico-basal ganglia loops; rabies virus retrograde transsynaptic tracing",
    "source_cluster_id": "cluster_06",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "A similar pattern of labeling was observed following M2 injections, where VS, DMS and TS can target M2 without receiving its direct inputs ( Figure 1G–1I , Figure 1—figure supplement 2C, D and J ), confirming an open loop in addition to the closed motor loop.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json",
  "effect_size": "",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-07",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-3023485dbad7"
  ],
  "source_span": "A similar pattern of labeling was observed following M2 injections, where VS, DMS and TS can target M2 without receiving its direct inputs ( Figure 1G–1I , Figure 1—figure supplement 2C, D and J ), confirming an open loop in addition to the closed motor loop.",
  "study_system": "mouse cortico-basal ganglia loops; rabies virus retrograde transsynaptic tracing",
  "evidence_refs": [
    {
      "ref": "paper:paper-3023485dbad7"
    }
  ],
  "section_title": "Parallel Loop Channels: Motor, Limbic, Associative, and Beyond the Classic Three",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Rabies virus tracing in mice showed neurons in ventral, dorsomedial, and tail striatum project transsynaptically to M1/M2 without receiving M1/M2 direct inputs, confirming open-loop architecture in parallel with the canonical closed motor loop.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-07",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}