Version history

{
  "scope": "juvenile mouse S1; whole-cell patch",
  "claim_text": "VIP-cluster interneurons in juvenile S1 show two distinct intrinsic firing behaviors: 68% (15/22) are adapting and 32% (7/22) are bursting; the adapting subset displays a characteristic post-spike sequence of first AHP → afterdepolarization (ADP) → late AHP after the first 2 action potentials in 8/15 cells — a signature seldom seen in PV or SST cells.",
  "raw_fields": {
    "n": 22,
    "doi": "10.1093/cercor/bhp310",
    "claim": "VIP-cluster interneurons in juvenile S1 show two distinct intrinsic firing behaviors: 68% (15/22) are adapting and 32% (7/22) are bursting; the adapting subset displays a characteristic post-spike sequence of first AHP → afterdepolarization (ADP) → late AHP after the first 2 action potentials in 8/15 cells — a signature seldom seen in PV or SST cells.",
    "title": null,
    "cite_key": "Vucurovic2010",
    "evidence": "whole-cell patch (Lee 2010 5HT3a:GFP)",
    "effect_size": "Adapting 68% (15/22); bursting 32% (7/22); ADP+late AHP in 8/15 adapting",
    "text_access": "fulltext",
    "study_system": "juvenile mouse S1; whole-cell patch",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 86,
    "claim_source_sentence": "Neurons of the VIP-cluster exhibit 2 types of firing behavior, adapting (n = 15/22, 68%) or bursting (n = 7/22, 32%).",
    "replication_evidence_dois": [
      "10.1093/cercor/bhv202"
    ],
    "effect_size_source_sentence": "Indeed, the first 2 action potentials of adapting VIP were followed by a first AHP component, an ADP, and a late AHP component ( n = 8/15)."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "Adapting 68% (15/22); bursting 32% (7/22); ADP+late AHP in 8/15 adapting",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-0336a131683f"
  ],
  "source_span": "Neurons of the VIP-cluster exhibit 2 types of firing behavior, adapting (n = 15/22, 68%) or bursting (n = 7/22, 32%).",
  "study_system": "juvenile mouse S1; whole-cell patch",
  "evidence_refs": [
    {
      "ref": "paper:paper-0336a131683f"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "whole-cell patch (Lee 2010 5HT3a:GFP)",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}