Microendoscopic imaging of D1- and D2-pathway SPNs during natural behavior show…

{
  "n": 10,
  "doi": "10.1016/j.neuron.2017.08.015",
  "claim": "Microendoscopic imaging of D1- and D2-pathway SPNs during natural behavior shows predominantly local correlations within each pathway and ensemble organization that maps action space, refining the simple opposing-pathway view.",
  "cite_key": "Klaus2017",
  "evidence": "",
  "effect_size": "predominantly local correlations within each pathway",
  "text_access": "fulltext",
  "study_system": "mice, microendoscopic imaging, D1- and D2-pathway SPNs in dorsal striatum during self-paced behavior",
  "source_cluster_id": "cluster_04",
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  "claim_source_sentence": "In addition, SPNs that were active during particular behaviors formed ensembles with a local bias yet a notable number of distant SPN pairs ( Figure 3 G; neurons that decreased firing rate did not show a significant local bias; see Figure S3 H), which contrasts with the idea of spatially compact and non-overlapping functional clusters.",
  "replication_evidence_dois": [
    "10.1038/nature11846",
    "10.1016/j.cell.2018.04.019"
  ],
  "effect_size_source_sentence": "Activity in both pathways showed predominantly local but also some long-range correlations."
}

[
  "paper:paper-10_1016_j_neuron_2017_08_015"
]

In addition, SPNs that were active during particular behaviors formed ensembles with a local bias yet a notable number of distant SPN pairs ( Figure 3 G; neurons that decreased firing rate did not show a significant local bias; see Figure S3 H), which contrasts with the idea of spatially compact and non-overlapping functional clusters.

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