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- Live5/17/2026, 4:35:28 PM
f3d3a6535877Content snapshot
{ "scope": "mice, microendoscopic imaging, D1- and D2-pathway SPNs in dorsal striatum during self-paced behavior", "claim_text": "Microendoscopic imaging of D1- and D2-pathway SPNs during natural behavior shows predominantly local correlations within each pathway and ensemble organization that maps action space, refining the simple opposing-pathway view.", "raw_fields": { "n": 10, "doi": "10.1016/j.neuron.2017.08.015", "claim": "Microendoscopic imaging of D1- and D2-pathway SPNs during natural behavior shows predominantly local correlations within each pathway and ensemble organization that maps action space, refining the simple opposing-pathway view.", "cite_key": "Klaus2017", "evidence": "", "effect_size": "predominantly local correlations within each pathway", "text_access": "fulltext", "study_system": "mice, microendoscopic imaging, D1- and D2-pathway SPNs in dorsal striatum during self-paced behavior", "source_cluster_id": "cluster_04", "replication_status": "replicated", "claim_source_sentence": "In addition, SPNs that were active during particular behaviors formed ensembles with a local bias yet a notable number of distant SPN pairs ( Figure 3 G; neurons that decreased firing rate did not show a significant local bias; see Figure S3 H), which contrasts with the idea of spatially compact and non-overlapping functional clusters.", "replication_evidence_dois": [ "10.1038/nature11846", "10.1016/j.cell.2018.04.019" ], "effect_size_source_sentence": "Activity in both pathways showed predominantly local but also some long-range correlations." }, "section_id": "section_04", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json", "effect_size": "predominantly local correlations within each pathway", "review_repo": "ComputationalReviewLoops", "section_ref": "wiki_page:computationalreviewloops-04", "source_kind": "review_finding", "source_path": "evidence/section_04_evidence_package.json", "source_refs": [ "paper:paper-10_1016_j_neuron_2017_08_015" ], "source_span": "In addition, SPNs that were active during particular behaviors formed ensembles with a local bias yet a notable number of distant SPN pairs ( Figure 3 G; neurons that decreased firing rate did not show a significant local bias; see Figure S3 H), which contrasts with the idea of spatially compact and non-overlapping functional clusters.", "study_system": "mice, microendoscopic imaging, D1- and D2-pathway SPNs in dorsal striatum during self-paced behavior", "evidence_refs": [ { "ref": "paper:paper-10_1016_j_neuron_2017_08_015" } ], "section_title": "Striatal Output Pathways: Direct, Indirect, and Beyond", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }, "evidence_summary": "", "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9", "replication_status": "replicated", "review_package_ref": "analysis_bundle:ab-d49e54403ef9", "source_artifact_ref": "wiki_page:computationalreviewloops-04", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json", "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }