Version history

{
  "scope": "mouse V1 in vivo 2-photon imaging + recurrent modeling",
  "claim_text": "Dipoppa et al. (2018) imaged Pyr/SST/VIP/PV cells simultaneously in mouse V1: in darkness their data fit the canonical VIP→SST disinhibition model, but during visual stimulation the model failed — locomotion increased SST responses to large stimuli and VIP responses to small ones — implying that effective synaptic connectivity is modulated by behavioral state and visual context.",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.neuron.2018.03.037",
    "claim": "Dipoppa et al. (2018) imaged Pyr/SST/VIP/PV cells simultaneously in mouse V1: in darkness their data fit the canonical VIP→SST disinhibition model, but during visual stimulation the model failed — locomotion increased SST responses to large stimuli and VIP responses to small ones — implying that effective synaptic connectivity is modulated by behavioral state and visual context.",
    "title": null,
    "cite_key": "Dipoppa2018",
    "evidence": "Simultaneous 2-photon Ca2+ imaging of four cell classes in mouse V1 across darkness and visual stimulus contexts; recurrent network modeling.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "mouse V1 in vivo 2-photon imaging + recurrent modeling",
    "target_section": "section_05",
    "_source_cluster": "cluster_01_molecular_taxonomy",
    "replication_status": "single_study",
    "_source_cluster_index": 71,
    "claim_source_sentence": "Our recordings in darkness were consistent with a \"disinhibitory\" model in which locomotion activates Vip cells, thus inhibiting Sst cells and disinhibiting Pyr cells."
  },
  "section_id": "section_02",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-02-classification",
  "source_kind": "review_finding",
  "source_path": "evidence/section_02_evidence_package.json",
  "source_refs": [
    "paper:paper-f457e091013f"
  ],
  "source_span": "Our recordings in darkness were consistent with a \"disinhibitory\" model in which locomotion activates Vip cells, thus inhibiting Sst cells and disinhibiting Pyr cells.",
  "study_system": "mouse V1 in vivo 2-photon imaging + recurrent modeling",
  "evidence_refs": [
    {
      "ref": "paper:paper-f457e091013f"
    }
  ],
  "section_title": "Molecular Identity and Transcriptomic Taxonomy",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Simultaneous 2-photon Ca2+ imaging of four cell classes in mouse V1 across darkness and visual stimulus contexts; recurrent network modeling.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-02-classification",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}