- claim_text
Dipoppa et al. (2018) imaged Pyr/SST/VIP/PV cells simultaneously in mouse V1: in darkness their data fit the canonical VIP→SST disinhibition model, but during visual stimulation the model failed — locomotion increased SST responses to large stimuli and VIP responses to small ones — implying that effective synaptic connectivity is modulated by behavioral state and visual context.
- raw_fields
{
"n": null,
"doi": "10.1016/j.neuron.2018.03.037",
"claim": "Dipoppa et al. (2018) imaged Pyr/SST/VIP/PV cells simultaneously in mouse V1: in darkness their data fit the canonical VIP→SST disinhibition model, but during visual stimulation the model failed — locomotion increased SST responses to large stimuli and VIP responses to small ones — implying that effective synaptic connectivity is modulated by behavioral state and visual context.",
"title": null,
"cite_key": "Dipoppa2018",
"evidence": "Simultaneous 2-photon Ca2+ imaging of four cell classes in mouse V1 across darkness and visual stimulus contexts; recurrent network modeling.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse V1 in vivo 2-photon imaging + recurrent modeling",
"target_section": "section_05",
"_source_cluster": "cluster_01_molecular_taxonomy",
"replication_status": "single_study",
"_source_cluster_index": 71,
"claim_source_sentence": "Our recordings in darkness were consistent with a \"disinhibitory\" model in which locomotion activates Vip cells, thus inhibiting Sst cells and disinhibiting Pyr cells."
}- source_refs
[
"paper:paper-f457e091013f"
]
- evidence_refs
[
{
"ref": "paper:paper-f457e091013f"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}