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- Live5/17/2026, 4:35:28 PM
e5bd6c62aac1Content snapshot
{ "scope": "mouse / computational model (GPe phase-resetting network)", "claim_text": "Phase-resetting modeling of mouse GPe networks shows that local inhibition slows and deregularizes background pallidal firing without producing periodic patterns, but in response to a shared brief inhibitory (striatal) input, neurons separate into a synchronized transient-rebound subpopulation and a sustained-inhibition subpopulation.", "raw_fields": { "n": null, "doi": "10.1007/s10827-022-00814-y", "claim": "Phase-resetting modeling of mouse GPe networks shows that local inhibition slows and deregularizes background pallidal firing without producing periodic patterns, but in response to a shared brief inhibitory (striatal) input, neurons separate into a synchronized transient-rebound subpopulation and a sustained-inhibition subpopulation.", "cite_key": "Olivares2022", "evidence": "Computational network simulation using phase-resetting model parameterized from mouse GPe slice recordings, with small-world and random connectivity.", "effect_size": "qualitative — input-driven dichotomization of GPe responses", "text_access": "abstract_only", "study_system": "mouse / computational model (GPe phase-resetting network)", "source_cluster_id": "cluster_03", "replication_status": "replication_unknown", "claim_source_sentence": "When stimulated by a shared inhibitory input, the individual neuron responses separated into two groups: one with a short and stereotyped period of inhibition followed by a transient increase in firing probability, and the other responding with a sustained inhibition.", "replication_evidence_dois": [], "effect_size_source_sentence": "In both networks, the resting activity was slowed and made more irregular by the local inhibition, but it did not show any periodic pattern." }, "section_id": "section_03", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json", "effect_size": "qualitative — input-driven dichotomization of GPe responses", "review_repo": "ComputationalReviewLoops", "section_ref": "wiki_page:computationalreviewloops-03", "source_kind": "review_finding", "source_path": "evidence/section_03_evidence_package.json", "source_refs": [ "paper:paper-00b26fc2cdcc" ], "source_span": "When stimulated by a shared inhibitory input, the individual neuron responses separated into two groups: one with a short and stereotyped period of inhibition followed by a transient increase in firing probability, and the other responding with a sustained inhibition.", "study_system": "mouse / computational model (GPe phase-resetting network)", "evidence_refs": [ { "ref": "paper:paper-00b26fc2cdcc" } ], "section_title": "The Cortico-Striatal Interface: Topography, Cell Types, and Input Convergence", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }, "evidence_summary": "Computational network simulation using phase-resetting model parameterized from mouse GPe slice recordings, with small-world and random connectivity.", "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d49e54403ef9", "source_artifact_ref": "wiki_page:computationalreviewloops-03", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json", "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }