Version history

{
  "scope": "layered spiking microcircuit model of somatosensory cortex (6 layers, 4 cell types)",
  "claim_text": "A six-layer somatosensory cortex model with PV, SST and VIP and short-term plasticity replicates layer-specific firing rates and shows the PV→SOM→VIP disinhibitory pathway substantially shapes pyramidal output when SOM is sufficiently active.",
  "raw_fields": {
    "n": null,
    "id": "cluster_11_finding_06",
    "doi": "10.1093/cercor/bhae378",
    "pmid": "39344196",
    "year": "2024",
    "claim": "A six-layer somatosensory cortex model with PV, SST and VIP and short-term plasticity replicates layer-specific firing rates and shows the PV→SOM→VIP disinhibitory pathway substantially shapes pyramidal output when SOM is sufficiently active.",
    "pmcid": "PMC11439972",
    "title": "A layered microcircuit model of somatosensory cortex with three interneuron types and cell-type-specific short-term plasticity.",
    "authors": "Jiang HJ, Qi G, Duarte R, Feldmeyer D, van Albada SJ.",
    "journal": "Cerebral cortex (New York, N.Y. : 1991)",
    "cite_key": "Jiang2024b",
    "evidence": "STP added to inhibitory and disinhibitory connections; ablation of disinhibitory motif quantifies its contribution.",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "layered spiking microcircuit model of somatosensory cortex (6 layers, 4 cell types)",
    "_source_cluster": "cluster_11_computational_models",
    "replication_status": "replicated_independent",
    "_source_cluster_index": 5,
    "claim_source_sentence": "This suggests that the effect of the PV SOM VIP pathway is significant when SOM cells are adequately active.",
    "replication_evidence_dois": [
      "10.1073/pnas.2504164122",
      "10.1371/journal.pcbi.1013469",
      "10.1371/journal.pcbi.1012036",
      "10.1007/s00422-021-00894-6",
      "10.7554/elife.77594"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_12",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "source_kind": "review_finding",
  "source_path": "evidence/section_12_evidence_package.json",
  "source_refs": [
    "paper:paper-8797c32e2132"
  ],
  "source_span": "This suggests that the effect of the PV SOM VIP pathway is significant when SOM cells are adequately active.",
  "study_system": "layered spiking microcircuit model of somatosensory cortex (6 layers, 4 cell types)",
  "evidence_refs": [
    {
      "ref": "paper:paper-8797c32e2132"
    }
  ],
  "section_title": "Computational Models of VIP Circuit Function",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "STP added to inhibitory and disinhibitory connections; ablation of disinhibitory motif quantifies its contribution.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated_independent",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}