Version history

{
  "scope": "Mouse (Cre driver lines, C57BL/6 background); whole-brain single-neuron axon reconstructions in sensorimotor cortex.",
  "claim_text": "A whole-morphology projectome of 1,023 IT and PT pyramidal neurons across six mouse sensorimotor subregions shows substantial hierarchical and layer differences in cortico-cortical axonal innervation, with medial motor cortex IT cells displaying more diverse projection patterns than lateral motor or sensory IT cells.",
  "raw_fields": {
    "n": 1023,
    "doi": "10.34133/research.0470",
    "claim": "A whole-morphology projectome of 1,023 IT and PT pyramidal neurons across six mouse sensorimotor subregions shows substantial hierarchical and layer differences in cortico-cortical axonal innervation, with medial motor cortex IT cells displaying more diverse projection patterns than lateral motor or sensory IT cells.",
    "cite_key": "Yao2024",
    "evidence": "Cre driver lines (IT and PT) plus high-resolution whole-brain imaging and single-neuron reconstruction across six sensorimotor subregions in mouse.",
    "effect_size": "1,023 single-neuron full morphologies across 6 sensorimotor subregions; medial-motor IT cells projected more diversely than lateral cells.",
    "text_access": "fulltext",
    "study_system": "Mouse (Cre driver lines, C57BL/6 background); whole-brain single-neuron axon reconstructions in sensorimotor cortex.",
    "argument_role": "supporting",
    "replication_status": "replicated",
    "claim_source_sentence": "We reconstructed the complete morphology of 1,023 pyramidal neurons and generated a projectome of 6 subregions within the sensorimotor cortex.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.1038/s41586-021-03941-1",
      "10.1038/s41586-021-03970-w"
    ],
    "effect_size_source_sentence": "We found that neurons located in the medial motor cortex had more diverse projection patterns than those in the lateral motor and sensory cortices."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "effect_size": "1,023 single-neuron full morphologies across 6 sensorimotor subregions; medial-motor IT cells projected more diversely than lateral cells.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-2e5a1035a887"
  ],
  "source_span": "We reconstructed the complete morphology of 1,023 pyramidal neurons and generated a projectome of 6 subregions within the sensorimotor cortex.",
  "study_system": "Mouse (Cre driver lines, C57BL/6 background); whole-brain single-neuron axon reconstructions in sensorimotor cortex.",
  "evidence_refs": [
    {
      "ref": "paper:paper-2e5a1035a887"
    }
  ],
  "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Cre driver lines (IT and PT) plus high-resolution whole-brain imaging and single-neuron reconstruction across six sensorimotor subregions in mouse.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}