Details
- scope
- Mouse (Cre driver lines, C57BL/6 background); whole-brain single-neuron axon reconstructions in sensorimotor cortex.
- section_id
- section_08
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
- effect_size
- 1,023 single-neuron full morphologies across 6 sensorimotor subregions; medial-motor IT cells projected more diversely than lateral cells.
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-08-cross-areal
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- We reconstructed the complete morphology of 1,023 pyramidal neurons and generated a projectome of 6 subregions within the sensorimotor cortex.
- study_system
- Mouse (Cre driver lines, C57BL/6 background); whole-brain single-neuron axon reconstructions in sensorimotor cortex.
- section_title
- 8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
- evidence_summary
- Cre driver lines (IT and PT) plus high-resolution whole-brain imaging and single-neuron reconstruction across six sensorimotor subregions in mouse.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-08-cross-areal
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- claim_text
A whole-morphology projectome of 1,023 IT and PT pyramidal neurons across six mouse sensorimotor subregions shows substantial hierarchical and layer differences in cortico-cortical axonal innervation, with medial motor cortex IT cells displaying more diverse projection patterns than lateral motor or sensory IT cells.
- raw_fields
{ "n": 1023, "doi": "10.34133/research.0470", "claim": "A whole-morphology projectome of 1,023 IT and PT pyramidal neurons across six mouse sensorimotor subregions shows substantial hierarchical and layer differences in cortico-cortical axonal innervation, with medial motor cortex IT cells displaying more diverse projection patterns than lateral motor or sensory IT cells.", "cite_key": "Yao2024", "evidence": "Cre driver lines (IT and PT) plus high-resolution whole-brain imaging and single-neuron reconstruction across six sensorimotor subregions in mouse.", "effect_size": "1,023 single-neuron full morphologies across 6 sensorimotor subregions; medial-motor IT cells projected more diversely than lateral cells.", "text_access": "fulltext", "study_system": "Mouse (Cre driver lines, C57BL/6 background); whole-brain single-neuron axon reconstructions in sensorimotor cortex.", "argument_role": "supporting", "replication_status": "replicated", "claim_source_sentence": "We reconstructed the complete morphology of 1,023 pyramidal neurons and generated a projectome of 6 subregions within the sensorimotor cortex.", "source_provenance_status": "ok", "replication_evidence_dois": [ "10.1038/s41586-021-03941-1", "10.1038/s41586-021-03970-w" ], "effect_size_source_sentence": "We found that neurons located in the medial motor cortex had more diverse projection patterns than those in the lateral motor and sensory cortices." }- source_refs
[ "paper:paper-2e5a1035a887" ]
- evidence_refs
[ { "ref": "paper:paper-2e5a1035a887" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }