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- Live5/17/2026, 4:35:28 PM
1ebb8c8c00b6Content snapshot
{ "scope": "Awake mouse dorsal cortex, wide-field calcium imaging, change-detection task", "claim_text": "Wide-field calcium imaging across mouse dorsal cortex during a visual change-detection task showed that covert antecedents of choice begin with confined modulation of visual cortex followed by sustained recruitment of secondary and primary motor cortex; recruitment of motor cortex by sensory evidence depended on temporal expectation — a quantitative cortex-wide trajectory of perceptual decision-making.", "raw_fields": { "n": 0, "doi": "10.1016/j.neuron.2021.03.031", "claim": "Wide-field calcium imaging across mouse dorsal cortex during a visual change-detection task showed that covert antecedents of choice begin with confined modulation of visual cortex followed by sustained recruitment of secondary and primary motor cortex; recruitment of motor cortex by sensory evidence depended on temporal expectation — a quantitative cortex-wide trajectory of perceptual decision-making.", "cite_key": "Orsolic2021", "evidence": "Wide-field dorsal-cortex calcium imaging during decision-making; dissociation of execution vs covert antecedent signals; expectation-dependent motor-cortex recruitment.", "effect_size": "visual→secondary→primary motor cortex cascade; motor recruitment modulated by temporal expectation", "text_access": "fulltext", "study_system": "Awake mouse dorsal cortex, wide-field calcium imaging, change-detection task", "argument_role": "supporting", "replication_status": "single-study", "claim_source_sentence": "Although signals related to execution of choice were widespread, fluctuations in sensory evidence in the absence of overt motor responses triggered a confined activity cascade, beginning with transient modulation of visual cortex and followed by sustained recruitment of the secondary and primary motor cortex.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "Activation of the motor cortex by sensory evidence was modulated by animals' expectation of when the stimulus was likely to change." }, "section_id": "section_15", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json", "effect_size": "visual→secondary→primary motor cortex cascade; motor recruitment modulated by temporal expectation", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits", "source_kind": "review_finding", "source_path": "evidence/section_15_evidence_package.json", "source_refs": [ "paper:paper-0461e198bfff" ], "source_span": "Although signals related to execution of choice were widespread, fluctuations in sensory evidence in the absence of overt motor responses triggered a confined activity cascade, beginning with transient modulation of visual cortex and followed by sustained recruitment of the secondary and primary motor cortex.", "study_system": "Awake mouse dorsal cortex, wide-field calcium imaging, change-detection task", "evidence_refs": [ { "ref": "paper:paper-0461e198bfff" } ], "section_title": "15. Methodological limits and emerging tools — what current mouse-cortex tools cannot yet measure about E→E recurrence (subthreshold network activity, fast plasticity in vivo, millimetre-scale dynamic connectomes), and what is on the near horizon", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Wide-field dorsal-cortex calcium imaging during decision-making; dissociation of execution vs covert antecedent signals; expectation-dependent motor-cortex recruitment.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single-study", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }