Version history

{
  "scope": "mouse V1, awake, two-photon all-optical + Neuropixels, illusory-contour task",
  "claim_text": "In mouse V1, two-photon holographic activation of illusory-contour 'IC-encoder' L2/3 neurons recapitulates the V1 representation of illusory contours through local pattern completion, indicating that recurrent intracortical excitation broadcasts top-down inference signals within V1.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41593-025-02055-5",
    "claim": "In mouse V1, two-photon holographic activation of illusory-contour 'IC-encoder' L2/3 neurons recapitulates the V1 representation of illusory contours through local pattern completion, indicating that recurrent intracortical excitation broadcasts top-down inference signals within V1.",
    "cite_key": "Shin2025b",
    "evidence": "Multi-Neuropixels recordings, mesoscale two-photon calcium imaging, and two-photon holographic optogenetic activation of identified IC-encoder neurons in mouse V1 during illusory-contour stimuli; comparison of evoked activity to true illusory representations.",
    "effect_size": "Holographic activation of small IC-encoder subset reproduces ensemble-level IC representation",
    "text_access": "fulltext",
    "study_system": "mouse V1, awake, two-photon all-optical + Neuropixels, illusory-contour task",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "We found that photoactivating IC-encoders recreated IC representations within V1 L2/3 through pattern completion.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.1016/j.cell.2019.05.045"
    ],
    "effect_size_source_sentence": "These results imply that neurons that encode top-down inference signals locally broadcast those signals through pattern completion."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "effect_size": "Holographic activation of small IC-encoder subset reproduces ensemble-level IC representation",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-d021eac95dc2"
  ],
  "source_span": "We found that photoactivating IC-encoders recreated IC representations within V1 L2/3 through pattern completion.",
  "study_system": "mouse V1, awake, two-photon all-optical + Neuropixels, illusory-contour task",
  "evidence_refs": [
    {
      "ref": "paper:paper-d021eac95dc2"
    }
  ],
  "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Multi-Neuropixels recordings, mesoscale two-photon calcium imaging, and two-photon holographic optogenetic activation of identified IC-encoder neurons in mouse V1 during illusory-contour stimuli; comparison of evoked activity to true illusory representations.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}