Details

scope
mouse somatosensory cortex, in vitro slice, pathway-specific ChR2
claim_text
Selective ChR2 expression in thalamocortical (TC) vs corticothalamic (CT) axons reveals that the two pathways drive functionally distinct feedforward circuits in mouse somatosensory cortex.
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-01-introduction
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
study_system
mouse somatosensory cortex, in vitro slice, pathway-specific ChR2
section_title
1. Introduction — what "excitatory recurrence" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis
evidence_summary
Selective ChR2 expression in TC vs CT axons combined with whole-cell recording in mouse cortical slices.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-01-introduction
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.neuron.2009.12.025",
  "claim": "Selective ChR2 expression in thalamocortical (TC) vs corticothalamic (CT) axons reveals that the two pathways drive functionally distinct feedforward circuits in mouse somatosensory cortex.",
  "cite_key": "Cruikshank2010",
  "evidence": "Selective ChR2 expression in TC vs CT axons combined with whole-cell recording in mouse cortical slices.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse somatosensory cortex, in vitro slice, pathway-specific ChR2",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We used this approach to examine and compare the functional properties of circuits engaged by TC and CT pathways, revealing differences in principles of feedforward processing that could not have been clearly determined using conventional techniques.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-046e316a15e6"
]
source_span
We used this approach to examine and compare the functional properties of circuits engaged by TC and CT pathways, revealing differences in principles of feedforward processing that could not have been clearly determined using conventional techniques.
evidence_refs
[
  {
    "ref": "paper:paper-046e316a15e6"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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