- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2009.12.025",
"claim": "Thalamocortical axons drive robust synaptic responses in cortical FS interneurons and excitatory cells but only weak responses in SOM interneurons; strong FS activation leads to feedforward inhibition in all cortical neuron types",
"evidence": "Optogenetic activation of ChR2-expressing thalamocortical vs corticothalamic pathways with paired recordings",
"effect_size": "FS cells received strong TC input; SOM cells received weak TC input",
"text_access": "fulltext",
"study_system": "mouse thalamocortical slice preparation",
"replication_status": "independently replicated",
"claim_source_sentence": "Laser stimulation of ChR2-expressing thalamocortical axons/terminals evoked robust synaptic responses in cortical excitatory cells and fast-spiking (FS) inhibitory interneurons, but only weak responses in somatostatin-containing interneurons. Strong FS cell activation led to feedforward inhibition in all cortical neuron types, including FS cells.",
"replication_evidence_dois": [
"10.1523/jneurosci.4727-04.2006",
"10.1523/JNEUROSCI.4565-14.2015"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-046e316a15e6"
]
- source_span
Laser stimulation of ChR2-expressing thalamocortical axons/terminals evoked robust synaptic responses in cortical excitatory cells and fast-spiking (FS) inhibitory interneurons, but only weak responses in somatostatin-containing interneurons. Strong FS cell activation led to feedforward inhibition in all cortical neuron types, including FS cells.
- evidence_refs
[
{
"ref": "paper:paper-046e316a15e6"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}