Version history
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- Live5/17/2026, 4:35:28 PM
9f942d848048Content snapshot
{ "scope": "Awake mouse, multi-structure extracellular recording", "claim_text": "The original Neuropixels probe integrates 384 simultaneously recorded channels addressing 960 sites on a single 10-mm shank, and two such probes recorded >700 well-isolated single neurons across five brain structures simultaneously in awake mouse — anchoring the present-day baseline for multi-area extracellular recording in mouse cortex.", "raw_fields": { "n": 700, "doi": "10.1038/nature24636", "claim": "The original Neuropixels probe integrates 384 simultaneously recorded channels addressing 960 sites on a single 10-mm shank, and two such probes recorded >700 well-isolated single neurons across five brain structures simultaneously in awake mouse — anchoring the present-day baseline for multi-area extracellular recording in mouse cortex.", "cite_key": "Jun2017", "evidence": "Original Neuropixels probe architecture; two-probe demonstration recorded >700 single units across 5 awake-mouse brain structures simultaneously.", "effect_size": ">700 well-isolated single neurons recorded simultaneously from 5 brain structures with two probes", "text_access": "abstract_only", "study_system": "Awake mouse, multi-structure extracellular recording", "argument_role": "supporting", "replication_status": "single-platform", "claim_source_sentence": "Each probe has 384 recording channels that can programmably address 960 complementary metal-oxide-semiconductor (CMOS) processing-compatible low-impedance TiN sites that tile a single 10-mm long, 70 × 20-μm cross-section shank.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Using two probes, more than 700 well-isolated single neurons were recorded simultaneously from five brain structures in an awake mouse." }, "section_id": "section_15", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json", "effect_size": ">700 well-isolated single neurons recorded simultaneously from 5 brain structures with two probes", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits", "source_kind": "review_finding", "source_path": "evidence/section_15_evidence_package.json", "source_refs": [ "paper:6f999156-d57b-49f0-a236-2c549c1190d6" ], "source_span": "Each probe has 384 recording channels that can programmably address 960 complementary metal-oxide-semiconductor (CMOS) processing-compatible low-impedance TiN sites that tile a single 10-mm long, 70 × 20-μm cross-section shank.", "study_system": "Awake mouse, multi-structure extracellular recording", "evidence_refs": [ { "ref": "paper:6f999156-d57b-49f0-a236-2c549c1190d6" } ], "section_title": "15. Methodological limits and emerging tools — what current mouse-cortex tools cannot yet measure about E→E recurrence (subthreshold network activity, fast plasticity in vivo, millimetre-scale dynamic connectomes), and what is on the near horizon", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Original Neuropixels probe architecture; two-probe demonstration recorded >700 single units across 5 awake-mouse brain structures simultaneously.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single-platform", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }