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- Live5/17/2026, 4:35:28 PM
635291e5b065Content snapshot
{ "scope": "Human EEG/MEG recordings, schizophrenia patients vs healthy controls", "claim_text": "Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.", "raw_fields": { "n": 2133, "doi": "10.1038/s41537-025-00596-z", "claim": "Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.", "evidence": "Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.", "effect_size": "Non-significant meta-analytic effect (N=211); 12 studies increased, 3 decreased, 13 no difference", "text_access": "fulltext", "study_system": "Human EEG/MEG recordings, schizophrenia patients vs healthy controls", "replication_status": "contested", "claim_source_sentence": "Results on power spectra were heterogeneous: in 12 studies gamma power was increased, involving the whole brain (N = 3), multiple regions (N = 6) or only frontal (N = 1), central (n = 1) and temporal (N = 1) areas; in 3 studies gamma power was reduced, involving multiple areas (N = 2) or the right temporal region (N = 1); one study revealed mixed results and 13 studies showed no differences.", "replication_evidence_dois": [ "10.1007/s00702-019-02080-2" ], "effect_size_source_sentence": "The meta-analysis on 4 studies (N = 211) showed non-significant differences between patients and controls and a large heterogeneity." }, "section_id": "section_13_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json", "effect_size": "Non-significant meta-analytic effect (N=211); 12 studies increased, 3 decreased, 13 no difference", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-13", "source_kind": "review_finding", "source_path": "evidence/section_13_evidence_package.json", "source_refs": [ "paper:paper-1aa62508f29b" ], "source_span": "Results on power spectra were heterogeneous: in 12 studies gamma power was increased, involving the whole brain (N = 3), multiple regions (N = 6) or only frontal (N = 1), central (n = 1) and temporal (N = 1) areas; in 3 studies gamma power was reduced, involving multiple areas (N = 2) or the right temporal region (N = 1); one study revealed mixed results and 13 studies showed no differences.", "study_system": "Human EEG/MEG recordings, schizophrenia patients vs healthy controls", "evidence_refs": [ { "ref": "paper:paper-1aa62508f29b" } ], "section_title": "Cross-Cluster Synthesis: What Replicates, What Is Contested, What Is Untested", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "contested", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-13", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }