Details

scope
Human EEG/MEG recordings, schizophrenia patients vs healthy controls
claim_text
Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.
section_id
section_13_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
effect_size
Non-significant meta-analytic effect (N=211); 12 studies increased, 3 decreased, 13 no difference
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-13
source_kind
review_finding
source_path
evidence/section_13_evidence_package.json
study_system
Human EEG/MEG recordings, schizophrenia patients vs healthy controls
section_title
Cross-Cluster Synthesis: What Replicates, What Is Contested, What Is Untested
evidence_summary
Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
contested
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-13
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_13_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 2133,
  "doi": "10.1038/s41537-025-00596-z",
  "claim": "Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.",
  "evidence": "Resting-state gamma-frequency alterations in schizophrenia are inconsistent across studies despite the PV-interneuron gamma hypothesis; meta-analysis on 4 studies (N=211) showed non-significant differences.",
  "effect_size": "Non-significant meta-analytic effect (N=211); 12 studies increased, 3 decreased, 13 no difference",
  "text_access": "fulltext",
  "study_system": "Human EEG/MEG recordings, schizophrenia patients vs healthy controls",
  "replication_status": "contested",
  "claim_source_sentence": "Results on power spectra were heterogeneous: in 12 studies gamma power was increased, involving the whole brain (N = 3), multiple regions (N = 6) or only frontal (N = 1), central (n = 1) and temporal (N = 1) areas; in 3 studies gamma power was reduced, involving multiple areas (N = 2) or the right temporal region (N = 1); one study revealed mixed results and 13 studies showed no differences.",
  "replication_evidence_dois": [
    "10.1007/s00702-019-02080-2"
  ],
  "effect_size_source_sentence": "The meta-analysis on 4 studies (N = 211) showed non-significant differences between patients and controls and a large heterogeneity."
}
source_refs
[
  "paper:paper-1aa62508f29b"
]
source_span
Results on power spectra were heterogeneous: in 12 studies gamma power was increased, involving the whole brain (N = 3), multiple regions (N = 6) or only frontal (N = 1), central (n = 1) and temporal (N = 1) areas; in 3 studies gamma power was reduced, involving multiple areas (N = 2) or the right temporal region (N = 1); one study revealed mixed results and 13 studies showed no differences.
evidence_refs
[
  {
    "ref": "paper:paper-1aa62508f29b"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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