- claim_text
Two-photon calcium imaging in mouse posterior parietal cortex during a delayed match-to-sample task identifies a subset of PPC neurons with joint directional and temporal selectivity; short-term memory errors are not driven by misencoding during the sample phase but by drift of PPC neural activity during the delay — a gradual divergence from the correct representation that predicts incorrect choices — direct evidence that drifting attractor-like persistent activity governs memory accuracy.
- raw_fields
{
"n": 0,
"doi": "10.1371/journal.pbio.3003359",
"claim": "Two-photon calcium imaging in mouse posterior parietal cortex during a delayed match-to-sample task identifies a subset of PPC neurons with joint directional and temporal selectivity; short-term memory errors are not driven by misencoding during the sample phase but by drift of PPC neural activity during the delay — a gradual divergence from the correct representation that predicts incorrect choices — direct evidence that drifting attractor-like persistent activity governs memory accuracy.",
"cite_key": "Choi2025c",
"evidence": "This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses. These results emphasize the importance of maintaining stable neural representations in the PPC for accurate STM.",
"effect_size": "",
"text_access": "abstract_only",
"study_system": "mouse posterior parietal cortex; two-photon calcium imaging in a delayed match-to-sample task with trial-by-trial decoding of neural drift",
"argument_role": "supporting",
"replication_status": "single_lab",
"claim_source_sentence": "Our findings reveal that these errors are more strongly associated with a drift in neural activity during the delay period.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-8a77f46a9951"
]
- evidence_refs
[
{
"ref": "paper:paper-8a77f46a9951"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}- evidence_summary
This drift leads to a gradual divergence away from the correct representation, ultimately leading to incorrect behavioral responses. These results emphasize the importance of maintaining stable neural representations in the PPC for accurate STM.