Version history

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  1. Live aef2b1bb7503
    5/17/2026, 4:35:28 PM
    Content snapshot
    {
      "scope": "mouse; PFC; Nature",
      "claim_text": "By investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC), that the mediodorsal thalamus sustains these representations without relaying categorica…",
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        "n": null,
        "doi": "10.1038/nature22073",
        "claim": "By investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC), that the mediodorsal thalamus sustains these representations without relaying categorica…",
        "cite_key": "Schmitt2017",
        "evidence": "Although interactions between the thalamus and cortex are critical for cognitive function, the exact contribution of the thalamus to these interactions remains unclear. Recent studies have shown diverse connectivity patterns across the thalamus, but whether this diversity translates to thalamic functions beyond relaying information to or between cortical regions is unknown. Here we show, by investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC)...",
        "effect_size": "Consistent with this idea, optogenetic PFC suppression in 100 ms bins across the delay resulted in identical behavioral effects throughout, while corresponding MD suppression resulted in weaker impact at the earliest and latest bins ().",
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        "claim_source_sentence": "Here we show, by investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC), that the mediodorsal thalamus sustains these representations without relaying categorical information.",
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        "replication_evidence_dois": [],
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        "effect_size_source_sentence": "Consistent with this idea, optogenetic PFC suppression in 100 ms bins across the delay resulted in identical behavioral effects throughout, while corresponding MD suppression resulted in weaker impact at the earliest and latest bins ()."
      },
      "section_id": "section_09",
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      "effect_size": "Consistent with this idea, optogenetic PFC suppression in 100 ms bins across the delay resulted in identical behavioral effects throughout, while corresponding MD suppression resulted in weaker impact at the earliest and latest bins ().",
      "review_repo": "ComputationalReviewRecurrence",
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      "study_system": "mouse; PFC; Nature",
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      "section_title": "9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation",
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        "notes": [
          "Local review repositories are read-only inputs.",
          "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
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      "evidence_summary": "Although interactions between the thalamus and cortex are critical for cognitive function, the exact contribution of the thalamus to these interactions remains unclear. Recent studies have shown diverse connectivity patterns across the thalamus, but whether this diversity translates to thalamic functions beyond relaying information to or between cortical regions is unknown. Here we show, by investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC)...",
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