Details
- scope
- mouse; PFC; Nature
- claim_text
- By investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC), that the mediodorsal thalamus sustains these representations without relaying categorica…
- section_id
- section_09
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
- effect_size
- Consistent with this idea, optogenetic PFC suppression in 100 ms bins across the delay resulted in identical behavioral effects throughout, while corresponding MD suppression resulted in weaker impact at the earliest and latest bins ().
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-09-amplification-isn
- source_kind
- review_finding
- source_path
- evidence/section_09_evidence_package.json
- source_span
- Here we show, by investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC), that the mediodorsal thalamus sustains these representations without relaying categorical information.
- study_system
- mouse; PFC; Nature
- section_title
- 9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- single_study
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-09-amplification-isn
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- raw_fields
{ "n": null, "doi": "10.1038/nature22073", "claim": "By investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC), that the mediodorsal thalamus sustains these representations without relaying categorica…", "cite_key": "Schmitt2017", "evidence": "Although interactions between the thalamus and cortex are critical for cognitive function, the exact contribution of the thalamus to these interactions remains unclear. Recent studies have shown diverse connectivity patterns across the thalamus, but whether this diversity translates to thalamic functions beyond relaying information to or between cortical regions is unknown. Here we show, by investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC)...", "effect_size": "Consistent with this idea, optogenetic PFC suppression in 100 ms bins across the delay resulted in identical behavioral effects throughout, while corresponding MD suppression resulted in weaker impact at the earliest and latest bins ().", "text_access": "fulltext", "study_system": "mouse; PFC; Nature", "argument_role": "supporting", "replication_status": "single_study", "claim_source_sentence": "Here we show, by investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC), that the mediodorsal thalamus sustains these representations without relaying categorical information.", "source_provenance_status": "ok", "replication_evidence_dois": [], "claim_rewritten_from_source": true, "effect_size_source_sentence": "Consistent with this idea, optogenetic PFC suppression in 100 ms bins across the delay resulted in identical behavioral effects throughout, while corresponding MD suppression resulted in weaker impact at the earliest and latest bins ()." }- source_refs
[ "paper:paper-1eecf1966d88" ]
- evidence_refs
[ { "ref": "paper:paper-1eecf1966d88" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }- evidence_summary
Although interactions between the thalamus and cortex are critical for cognitive function, the exact contribution of the thalamus to these interactions remains unclear. Recent studies have shown diverse connectivity patterns across the thalamus, but whether this diversity translates to thalamic functions beyond relaying information to or between cortical regions is unknown. Here we show, by investigating the representation of two rules used to guide attention in the mouse prefrontal cortex (PFC)...