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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse primary visual cortex (V1) — in vivo optogenetics + LFP, plus computational model", "claim_text": "VIP disinhibitory interneurons in mouse cortex linearly scale local gamma power without altering its stimulus tuning, while suppressing long-range gamma coherence between regions processing non-matched stimuli.", "raw_fields": { "n": null, "doi": "10.1016/j.neuron.2022.10.036", "pmid": "36384143", "year": "2023", "claim": "VIP disinhibitory interneurons in mouse cortex linearly scale local gamma power without altering its stimulus tuning, while suppressing long-range gamma coherence between regions processing non-matched stimuli.", "pmcid": "PMC9898108", "title": "Cortical VIP neurons locally control the gain but globally control the coherence of gamma band rhythms.", "authors": "", "journal": "", "cite_key": "Veit2023", "evidence": "Optogenetic activation of VIP cells in mouse V1 modulates gamma power locally and inter-areal gamma coherence; computational model with VIP→SST inhibition reproduces this dual role.", "cluster_id": "cluster_09_oscillations", "effect_size": "VIP cells linearly scale gamma power locally and globally tune gamma coherence between regions", "figure_data": [], "text_access": "abstract_only", "study_system": "mouse primary visual cortex (V1) — in vivo optogenetics + LFP, plus computational model", "cited_by_count": 84, "_source_cluster": "cluster_09_oscillations", "replication_status": "independently_replicated", "_source_cluster_index": 0, "claim_source_sentence": "Combining electrophysiology, optogenetics, and computational modeling, we found that VIP disinhibitory interneurons in mouse cortex linearly scale gamma power locally without changing its stimulus tuning. Conversely, they suppress long-range synchronization when two regions process non-matched stimuli, tuning gamma coherence globally.", "replication_evidence_dois": [ "10.1101/2021.05.20.444979", "10.1093/cercor/bhac355", "10.7554/elife.77594" ], "effect_size_source_sentence": "VIP disinhibitory interneurons in mouse cortex linearly scale gamma power locally without changing its stimulus tuning." }, "section_id": "section_10", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json", "effect_size": "VIP cells linearly scale gamma power locally and globally tune gamma coherence between regions", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-10-oscillatory-dynamics", "source_kind": "review_finding", "source_path": "evidence/section_10_evidence_package.json", "source_refs": [ "paper:paper-d895aafe5d83" ], "source_span": "Combining electrophysiology, optogenetics, and computational modeling, we found that VIP disinhibitory interneurons in mouse cortex linearly scale gamma power locally without changing its stimulus tuning. Conversely, they suppress long-range synchronization when two regions process non-matched stimuli, tuning gamma coherence globally.", "study_system": "mouse primary visual cortex (V1) — in vivo optogenetics + LFP, plus computational model", "evidence_refs": [ { "ref": "paper:paper-d895aafe5d83" } ], "section_title": "Oscillatory Dynamics and Temporal Coordination", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Optogenetic activation of VIP cells in mouse V1 modulates gamma power locally and inter-areal gamma coherence; computational model with VIP→SST inhibition reproduces this dual role.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "independently_replicated", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-10-oscillatory-dynamics", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }