Details
- scope
- Young-adult mouse sensory cortex (visual, auditory, somatosensory), L5 pyramidal neurons (in vivo two-photon)
- section_id
- section_12
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_12_evidence_package.json
- effect_size
- >80% spine and bouton persistence over 3 weeks
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-12-plasticity
- source_kind
- review_finding
- source_path
- evidence/section_12_evidence_package.json
- source_span
- Both terminals and spines were relatively stable, with >80% persisting over a 3 week period in all sensory regions.
- study_system
- Young-adult mouse sensory cortex (visual, auditory, somatosensory), L5 pyramidal neurons (in vivo two-photon)
- section_title
- 12. Plasticity at E→E synapses in mouse — Hebbian, STDP, behavioural-time-scale plasticity; how plasticity shapes the recurrent matrix during learning
- evidence_summary
- Chronic in vivo two-photon imaging in P40-P61 mice across visual, auditory, somatosensory cortices showed >80% 3-week persistence; juvenile P28 spine motility was lowest in visual cortex and unaltered by neonatal visual→auditory rewiring.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-12-plasticity
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_12_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- claim_text
In young-adult mouse sensory cortex, >80% of both axonal boutons and dendritic spines persist over a 3-week imaging period, with axon terminals more stable than spines, suggesting much of adult plasticity occurs through strength changes at existing synapses.
- raw_fields
{ "n": 0, "doi": "10.1523/jneurosci.4454-05.2006", "claim": "In young-adult mouse sensory cortex, >80% of both axonal boutons and dendritic spines persist over a 3-week imaging period, with axon terminals more stable than spines, suggesting much of adult plasticity occurs through strength changes at existing synapses.", "cite_key": "Majewska2006", "evidence": "Chronic in vivo two-photon imaging in P40-P61 mice across visual, auditory, somatosensory cortices showed >80% 3-week persistence; juvenile P28 spine motility was lowest in visual cortex and unaltered by neonatal visual→auditory rewiring.", "effect_size": ">80% spine and bouton persistence over 3 weeks", "text_access": "abstract_only", "study_system": "Young-adult mouse sensory cortex (visual, auditory, somatosensory), L5 pyramidal neurons (in vivo two-photon)", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Both terminals and spines were relatively stable, with >80% persisting over a 3 week period in all sensory regions.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Both terminals and spines were relatively stable, with >80% persisting over a 3 week period in all sensory regions." }- source_refs
[ "paper:paper-904b9c8800c1" ]
- evidence_refs
[ { "ref": "paper:paper-904b9c8800c1" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }