Version history

{
  "scope": "Mouse primary visual cortex with single-cell rabies-GCaMP6s tracing",
  "claim_text": "Single-cell-initiated, monosynaptically-restricted rabies tracing combined with GCaMP6s allows in vivo functional imaging of presynaptic networks of individual L2/3 cortical pyramidal cells in mouse V1, revealing layer-specific functional modules with both feature-locked and feature-variant network architectures.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1126/science.aab1687",
    "claim": "Single-cell-initiated, monosynaptically-restricted rabies tracing combined with GCaMP6s allows in vivo functional imaging of presynaptic networks of individual L2/3 cortical pyramidal cells in mouse V1, revealing layer-specific functional modules with both feature-locked and feature-variant network architectures.",
    "cite_key": "Wertz2015",
    "evidence": "Single-starter-cell rabies-GCaMP6s + 2-photon imaging of presynaptic activity.",
    "effect_size": "2/3",
    "text_access": "abstract_only",
    "study_system": "Mouse primary visual cortex with single-cell rabies-GCaMP6s tracing",
    "source_cluster_id": "cluster_10",
    "replication_status": "single_study",
    "claim_source_sentence": "We used single-cell-initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s to image, in vivo, the visual motion-evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "We used single-cell-initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s to image, in vivo, the visual motion-evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex."
  },
  "section_id": "section_11",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json",
  "effect_size": "2/3",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-11",
  "source_kind": "review_finding",
  "source_path": "evidence/section_11_evidence_package.json",
  "source_refs": [
    "paper:paper-39dfc6d6e34c"
  ],
  "source_span": "We used single-cell-initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s to image, in vivo, the visual motion-evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex.",
  "study_system": "Mouse primary visual cortex with single-cell rabies-GCaMP6s tracing",
  "evidence_refs": [
    {
      "ref": "paper:paper-39dfc6d6e34c"
    }
  ],
  "section_title": "Cell-Type-Specific Dissection of Loop Circuits (Opto/Chemo/Tracing)",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Single-starter-cell rabies-GCaMP6s + 2-photon imaging of presynaptic activity.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-11",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_11_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}