- claim_text
Single-cell-initiated, monosynaptically-restricted rabies tracing combined with GCaMP6s allows in vivo functional imaging of presynaptic networks of individual L2/3 cortical pyramidal cells in mouse V1, revealing layer-specific functional modules with both feature-locked and feature-variant network architectures.
- raw_fields
{
"n": 0,
"doi": "10.1126/science.aab1687",
"claim": "Single-cell-initiated, monosynaptically-restricted rabies tracing combined with GCaMP6s allows in vivo functional imaging of presynaptic networks of individual L2/3 cortical pyramidal cells in mouse V1, revealing layer-specific functional modules with both feature-locked and feature-variant network architectures.",
"cite_key": "Wertz2015",
"evidence": "Single-starter-cell rabies-GCaMP6s + 2-photon imaging of presynaptic activity.",
"effect_size": "2/3",
"text_access": "abstract_only",
"study_system": "Mouse primary visual cortex with single-cell rabies-GCaMP6s tracing",
"source_cluster_id": "cluster_10",
"replication_status": "single_study",
"claim_source_sentence": "We used single-cell-initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s to image, in vivo, the visual motion-evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "We used single-cell-initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s to image, in vivo, the visual motion-evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex."
}- source_refs
[
"paper:paper-39dfc6d6e34c"
]
- source_span
We used single-cell-initiated, monosynaptically restricted retrograde transsynaptic tracing with rabies viruses expressing GCaMP6s to image, in vivo, the visual motion-evoked activity of individual layer 2/3 pyramidal neurons and their presynaptic networks across layers in mouse primary visual cortex.
- evidence_refs
[
{
"ref": "paper:paper-39dfc6d6e34c"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}