Version history

{
  "scope": "mouse S1 cortex; Vip-IRES-Cre × tdTomato; ex vivo patch-clamp",
  "claim_text": "VIP interneurons in mouse somatosensory cortex mature postnatally with subtype-asymmetric synaptic ontogenesis: mEPSC frequency rises before P8-10 (excitatory innervation first), mIPSC frequency rises by P14-16 (delayed inhibitory integration), and the E/I charge-transfer ratio remains constant across development; synaptic kinetics accelerate while presynaptic release probability decreases by adulthood.",
  "raw_fields": {
    "n": null,
    "doi": "10.1111/apha.14265",
    "claim": "VIP interneurons in mouse somatosensory cortex mature postnatally with subtype-asymmetric synaptic ontogenesis: mEPSC frequency rises before P8-10 (excitatory innervation first), mIPSC frequency rises by P14-16 (delayed inhibitory integration), and the E/I charge-transfer ratio remains constant across development; synaptic kinetics accelerate while presynaptic release probability decreases by adulthood.",
    "title": null,
    "cite_key": "Simacek2025b",
    "evidence": "Patch-clamp electrophysiology of VIP-INs in Vip-IRES-cre × tdTomato mouse somatosensory cortex at P3-4, P8-10, P14-16, P30-36.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "mouse S1 cortex; Vip-IRES-Cre × tdTomato; ex vivo patch-clamp",
    "target_section": "section_03",
    "_source_cluster": "cluster_01_molecular_taxonomy",
    "replication_status": "replication_unknown",
    "_source_cluster_index": 118,
    "claim_source_sentence": "mEPSC frequency increased before P8-10, while mIPSC frequency increased at P14-16. Only mIPSC kinetics became accelerated, and the E/I ratio of synaptic inputs, defined as a ratio of mEPSC to mIPSC charge transfer, remained constant throughout the investigated developmental stages.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_01",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-01-introduction",
  "source_kind": "review_finding",
  "source_path": "evidence/section_01_evidence_package.json",
  "source_refs": [
    "paper:paper-b709c20d2cb8"
  ],
  "source_span": "mEPSC frequency increased before P8-10, while mIPSC frequency increased at P14-16. Only mIPSC kinetics became accelerated, and the E/I ratio of synaptic inputs, defined as a ratio of mEPSC to mIPSC charge transfer, remained constant throughout the investigated developmental stages.",
  "study_system": "mouse S1 cortex; Vip-IRES-Cre × tdTomato; ex vivo patch-clamp",
  "evidence_refs": [
    {
      "ref": "paper:paper-b709c20d2cb8"
    }
  ],
  "section_title": "Introduction",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Patch-clamp electrophysiology of VIP-INs in Vip-IRES-cre × tdTomato mouse somatosensory cortex at P3-4, P8-10, P14-16, P30-36.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-01-introduction",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}