Details

scope
Awake head-fixed mouse; multi-slice fUS imaging through intact skull
section_id
section_16
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json
effect_size
>10% CBV increase during visual stimulation vs baseline
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-16-synthesis
source_kind
review_finding
source_path
evidence/section_16_evidence_package.json
source_span
Significant activation was detected along the whole visual pathway, at both single and group levels, with more than 10% of augmentation of the cerebral blood volume (CBV) signal during the visual stimulation compared to baseline.
study_system
Awake head-fixed mouse; multi-slice fUS imaging through intact skull
section_title
16. Synthesis — which computational claims the mouse-cortex E→E empirical record actually supports, where the bottleneck observations are, and what an inhibition-free, single-species, basic-research analytic framing misses
evidence_summary
Quantifies the mesoscale hemodynamic-imaging baseline that frames what Neuropixels and voltage imaging contribute differently.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-16-synthesis
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Simultaneous multi-slice functional-ultrasound imaging can map brain-wide hemodynamic functional networks in awake mice through intact skull, but its single-trial blood-volume readout (>10% increase during visual stimulation) does not resolve single neurons — illustrating the resolution gap between mesoscale-FC and cellular E→E approaches.
raw_fields
{
  "n": 0,
  "doi": "10.1162/imag_a_00030",
  "claim": "Simultaneous multi-slice functional-ultrasound imaging can map brain-wide hemodynamic functional networks in awake mice through intact skull, but its single-trial blood-volume readout (>10% increase during visual stimulation) does not resolve single neurons — illustrating the resolution gap between mesoscale-FC and cellular E→E approaches.",
  "cite_key": "Bertolo2023",
  "evidence": "Quantifies the mesoscale hemodynamic-imaging baseline that frames what Neuropixels and voltage imaging contribute differently.",
  "effect_size": ">10% CBV increase during visual stimulation vs baseline",
  "text_access": "abstract_only",
  "study_system": "Awake head-fixed mouse; multi-slice fUS imaging through intact skull",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "Significant activation was detected along the whole visual pathway, at both single and group levels, with more than 10% of augmentation of the cerebral blood volume (CBV) signal during the visual stimulation compared to baseline.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Significant activation was detected along the whole visual pathway, at both single and group levels, with more than 10% of augmentation of the cerebral blood volume (CBV) signal during the visual stimulation compared to baseline."
}
source_refs
[
  "paper:paper-7bd9a028fc66"
]
evidence_refs
[
  {
    "ref": "paper:paper-7bd9a028fc66"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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