Details

scope
rodent SNr in vitro + modeling
claim_text
Substantia nigra pars reticulata neurons fire rapidly during brief pauses in pallido-nigral inhibition despite lacking hyperpolarization-activated rebound currents; their phase-resetting curves explain rapid disinhibition.
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_01_evidence_package.json
effect_size
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-01
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
study_system
rodent SNr in vitro + modeling
section_title
Introduction: Swanson's Loop Hypothesis and Its Intellectual Lineage
evidence_summary
In vitro slice recordings + computational modeling of phase-resetting curves.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-01
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_01_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1152/jn.00678.2019",
  "claim": "Substantia nigra pars reticulata neurons fire rapidly during brief pauses in pallido-nigral inhibition despite lacking hyperpolarization-activated rebound currents; their phase-resetting curves explain rapid disinhibition.",
  "cite_key": "Simmons2020",
  "evidence": "In vitro slice recordings + computational modeling of phase-resetting curves.",
  "effect_size": "",
  "text_access": "abstract_only",
  "study_system": "rodent SNr in vitro + modeling",
  "source_cluster_id": "cluster_01",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Despite lacking any hyperpolarization-activated rebound currents, they fire quickly to even brief pauses in the pallido-nigral inhibition. The mechanism of their rapid disinhibitory response is explained by features of their phase-resetting curves.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-30a18a3f0eb7"
]
source_span
Despite lacking any hyperpolarization-activated rebound currents, they fire quickly to even brief pauses in the pallido-nigral inhibition. The mechanism of their rapid disinhibitory response is explained by features of their phase-resetting curves.
evidence_refs
[
  {
    "ref": "paper:paper-30a18a3f0eb7"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.