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- Live5/17/2026, 4:35:28 PM
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{ "scope": "single neuron models (multiple types) and striatal microcircuit model with FS interneurons", "claim_text": "GABAergic synaptic inputs produce non-monotonic effects on neuronal firing: small GABA conductances are excitatory while large conductances are inhibitory for intermediate GABA reversal potentials", "raw_fields": { "n": 0, "doi": "10.1371/journal.pcbi.1010226", "claim": "GABAergic synaptic inputs produce non-monotonic effects on neuronal firing: small GABA conductances are excitatory while large conductances are inhibitory for intermediate GABA reversal potentials", "evidence": "Analytical calculations and numerical simulations across multiple single-neuron models; striatal microcircuit model", "effect_size": null, "text_access": "fulltext", "study_system": "single neuron models (multiple types) and striatal microcircuit model with FS interneurons", "replication_status": "replication_unknown", "claim_source_sentence": "In the non-monotonic regime, small GABA conductances have an excitatory effect while large GABA conductances show an inhibitory effect.", "replication_evidence_dois": [], "effect_size_source_sentence": null }, "section_id": "section_12_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-12", "source_kind": "review_finding", "source_path": "evidence/section_12_evidence_package.json", "source_refs": [ "paper:paper-c9afbde00fc1" ], "source_span": "In the non-monotonic regime, small GABA conductances have an excitatory effect while large GABA conductances show an inhibitory effect.", "study_system": "single neuron models (multiple types) and striatal microcircuit model with FS interneurons", "evidence_refs": [ { "ref": "paper:paper-c9afbde00fc1" } ], "section_title": "Computational Models of PV Circuit Function", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Analytical calculations and numerical simulations across multiple single-neuron models; striatal microcircuit model", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-12", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }