Version history

{
  "scope": "mouse primary visual cortex (V1) L2/3 in vivo",
  "claim_text": "Nuclear-localized GCaMP two-photon imaging in mouse V1 reveals that the salt-and-pepper organization of orientation tuning hides a fine-scale 'micro-clustered' organization: extremely-close-neighbour neuron pairs share strongly correlated orientation tuning while distant pairs are essentially uncorrelated, consistent with recurrent excitatory-coupling-dominated wiring rather than feedforward inheritance.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1101/2025.02.11.637768",
    "claim": "Nuclear-localized GCaMP two-photon imaging in mouse V1 reveals that the salt-and-pepper organization of orientation tuning hides a fine-scale 'micro-clustered' organization: extremely-close-neighbour neuron pairs share strongly correlated orientation tuning while distant pairs are essentially uncorrelated, consistent with recurrent excitatory-coupling-dominated wiring rather than feedforward inheritance.",
    "cite_key": "Yu2025",
    "evidence": "Two-photon calcium imaging in mouse V1 using a novel nuclear-localized GCaMP indicator with circuit-based recurrent network modeling.",
    "effect_size": "qualitative — short-range orientation micro-clustering hidden in classical salt-and-pepper view",
    "text_access": "fulltext",
    "study_system": "mouse primary visual cortex (V1) L2/3 in vivo",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "neuron pairs that are extremely close have strongly correlated orientation tuning, indicating a narrow yet strong spatially clustered organization of orientation preference, which we term 'micro-clustered' organization",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "we term 'micro-clustered' organization"
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "qualitative — short-range orientation micro-clustering hidden in classical salt-and-pepper view",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-382052e33d4f"
  ],
  "source_span": "neuron pairs that are extremely close have strongly correlated orientation tuning, indicating a narrow yet strong spatially clustered organization of orientation preference, which we term 'micro-clustered' organization",
  "study_system": "mouse primary visual cortex (V1) L2/3 in vivo",
  "evidence_refs": [
    {
      "ref": "paper:paper-382052e33d4f"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon calcium imaging in mouse V1 using a novel nuclear-localized GCaMP indicator with circuit-based recurrent network modeling.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}