Version history

{
  "scope": "Mouse forelimb motor cortex (M1); ex vivo slice physiology",
  "claim_text": "In mouse forelimb motor cortex, intracortical excitatory connectivity is asymmetric across layer-6 corticothalamic (CT), intratelencephalic (IT), and layer-5 pyramidal-tract (PT) projection classes: CT↔IT connections are limited to L6 IT and CT↔PT connectivity is strikingly weak.",
  "raw_fields": {
    "n": null,
    "doi": "10.1523/jneurosci.4023-14.2015",
    "claim": "In mouse forelimb motor cortex, intracortical excitatory connectivity is asymmetric across layer-6 corticothalamic (CT), intratelencephalic (IT), and layer-5 pyramidal-tract (PT) projection classes: CT↔IT connections are limited to L6 IT and CT↔PT connectivity is strikingly weak.",
    "cite_key": "Yamawaki2015",
    "evidence": "Channelrhodopsin-2-assisted circuit mapping plus paired recordings in M1 of mouse, dissecting CT/IT/PT connectivity and CT–thalamus reciprocal connections.",
    "effect_size": "Strong CT↔CT and CT↔IT (L6) connectivity; near-absent CT↔PT excitation; M1-CT and ventrolateral thalamus largely unconnected in either direction.",
    "text_access": "abstract_only",
    "study_system": "Mouse forelimb motor cortex (M1); ex vivo slice physiology",
    "argument_role": "supporting",
    "replication_status": "single-study",
    "claim_source_sentence": "Stimulating and recording from CT, intratelencephalic (IT), and pyramidal tract (PT) projection neurons, we found strong CT↔ CT and CT↔ IT connections; however, CT→IT connections were limited to IT neurons in layer 6, not 5B.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "There was strikingly little CT↔ PT excitatory connectivity."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "effect_size": "Strong CT↔CT and CT↔IT (L6) connectivity; near-absent CT↔PT excitation; M1-CT and ventrolateral thalamus largely unconnected in either direction.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-77ff3f69a352"
  ],
  "source_span": "Stimulating and recording from CT, intratelencephalic (IT), and pyramidal tract (PT) projection neurons, we found strong CT↔ CT and CT↔ IT connections; however, CT→IT connections were limited to IT neurons in layer 6, not 5B.",
  "study_system": "Mouse forelimb motor cortex (M1); ex vivo slice physiology",
  "evidence_refs": [
    {
      "ref": "paper:paper-77ff3f69a352"
    }
  ],
  "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Channelrhodopsin-2-assisted circuit mapping plus paired recordings in M1 of mouse, dissecting CT/IT/PT connectivity and CT–thalamus reciprocal connections.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single-study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}