Details

scope
mouse entorhinal cortex acute slices
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
effect_size
81.4% prediction accuracy from 5 intrinsic features
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-05-electrophysiology
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
Finally, we reduced the complex multidimensional space of intrinsic properties to the most salient five that predicted the cellular biomolecular identity with 81.4% accuracy.
study_system
mouse entorhinal cortex acute slices
section_title
Intrinsic Electrophysiology
evidence_summary
mouse EC acute slices; whole-cell recordings of stellate, pyramidal, and 6 molecularly defined interneuron classes; hierarchical clustering
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-05-electrophysiology
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
In mouse entorhinal cortex, hierarchical clustering of intrinsic properties yields physiologically defined cell types that align with molecular identity (VIP, SST, 5HT3a-R, NPY-NGF, NPY-non-NGF, RCAN2), and five intrinsic features predict molecular identity with 81.4% accuracy.
raw_fields
{
  "n": null,
  "doi": "10.1093/cercor/bhw143",
  "claim": "In mouse entorhinal cortex, hierarchical clustering of intrinsic properties yields physiologically defined cell types that align with molecular identity (VIP, SST, 5HT3a-R, NPY-NGF, NPY-non-NGF, RCAN2), and five intrinsic features predict molecular identity with 81.4% accuracy.",
  "title": null,
  "cite_key": "Ferrante2016",
  "evidence": "mouse EC acute slices; whole-cell recordings of stellate, pyramidal, and 6 molecularly defined interneuron classes; hierarchical clustering",
  "effect_size": "81.4% prediction accuracy from 5 intrinsic features",
  "text_access": "abstract_only",
  "study_system": "mouse entorhinal cortex acute slices",
  "_source_cluster": "cluster_04_intrinsic_electrophysiology",
  "replication_status": "replicated",
  "_source_cluster_index": 4,
  "claim_source_sentence": "Finally, we reduced the complex multidimensional space of intrinsic properties to the most salient five that predicted the cellular biomolecular identity with 81.4% accuracy.",
  "replication_evidence_dois": [
    "10.1126/science.adf6484",
    "10.1016/j.neuron.2021.08.030"
  ],
  "effect_size_source_sentence": "Finally, we reduced the complex multidimensional space of intrinsic properties to the most salient five that predicted the cellular biomolecular identity with 81.4% accuracy."
}
source_refs
[
  "paper:paper-2ac5acbd638e"
]
evidence_refs
[
  {
    "ref": "paper:paper-2ac5acbd638e"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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