Version history

{
  "scope": "mouse V1, L2/3 pyramidal neurons; in vivo 2-photon imaging plus in vitro paired patch recordings",
  "claim_text": "Synaptic strengths between L2/3 V1 pyramidal pairs follow a heavy-tailed distribution; the few strong connections link neurons with the most correlated visual responses, while weak connections dominate uncorrelated pairs.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/nature14182",
    "claim": "Synaptic strengths between L2/3 V1 pyramidal pairs follow a heavy-tailed distribution; the few strong connections link neurons with the most correlated visual responses, while weak connections dominate uncorrelated pairs.",
    "cite_key": "Cossell2015",
    "evidence": "Paired recordings between L2/3 pyramidal neurons whose visual response correlations were measured in vivo. Strong-connection rule extracted from EPSP-amplitude distributions vs signal correlation.",
    "effect_size": "Connection amplitudes span ~2 orders of magnitude; strongest tail confined to highly correlated pairs",
    "text_access": "abstract_only",
    "study_system": "mouse V1, L2/3 pyramidal neurons; in vivo 2-photon imaging plus in vitro paired patch recordings",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Here we reveal that the strength of connections between layer 2/3 (L2/3) pyramidal neurons in mouse primary visual cortex (V1) obeys a simple rule--the few strong connections occur between neurons with most correlated responses, while only weak connections link neurons with uncorrelated responses.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/nature09880",
      "10.1038/nature17192"
    ],
    "effect_size_source_sentence": "Excitatory connection amplitudes between pairs of cortical neurons vary over two orders of magnitude, comprising only very few strong connections among many weaker ones."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "effect_size": "Connection amplitudes span ~2 orders of magnitude; strongest tail confined to highly correlated pairs",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-c4ad527c9bfb"
  ],
  "source_span": "Here we reveal that the strength of connections between layer 2/3 (L2/3) pyramidal neurons in mouse primary visual cortex (V1) obeys a simple rule--the few strong connections occur between neurons with most correlated responses, while only weak connections link neurons with uncorrelated responses.",
  "study_system": "mouse V1, L2/3 pyramidal neurons; in vivo 2-photon imaging plus in vitro paired patch recordings",
  "evidence_refs": [
    {
      "ref": "paper:paper-c4ad527c9bfb"
    }
  ],
  "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Paired recordings between L2/3 pyramidal neurons whose visual response correlations were measured in vivo. Strong-connection rule extracted from EPSP-amplitude distributions vs signal correlation.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}