Version history

{
  "scope": "review of mouse cortex VIP/CCK studies",
  "claim_text": "VIP-expressing interneurons split into transcriptionally and morphologically distinct sub-populations: classic bipolar VIP+ cells (vertically oriented axons) form one cluster, while multipolar VIP+/CCK+ cells are basket cells transcriptionally closer to other CCK+ baskets lacking VIP, with VIP+/CCK+ baskets enriched in supragranular layers and CCK+/VIP- baskets enriched in L5/6.",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.neuron.2018.10.009",
    "claim": "VIP-expressing interneurons split into transcriptionally and morphologically distinct sub-populations: classic bipolar VIP+ cells (vertically oriented axons) form one cluster, while multipolar VIP+/CCK+ cells are basket cells transcriptionally closer to other CCK+ baskets lacking VIP, with VIP+/CCK+ baskets enriched in supragranular layers and CCK+/VIP- baskets enriched in L5/6.",
    "title": null,
    "cite_key": "Lim2018",
    "evidence": "review of Lim 2018 + He 2016 + Tasic 2017 transcriptomic and morphological studies",
    "effect_size": "qualitative laminar enrichment differences",
    "text_access": "fulltext",
    "study_system": "review of mouse cortex VIP/CCK studies",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 64,
    "claim_source_sentence": "CCK+ basket cells that co-express VIP have a small soma and are particularly abundant in supragranular layers of the cortex, whereas CCK+ basket cells lacking VIP are enriched in layers 5 and 6.",
    "replication_evidence_dois": [
      "10.1038/s41586-018-0654-5",
      "10.1016/j.cell.2020.09.057"
    ],
    "effect_size_source_sentence": "Multipolar VIP+ cells are transcriptionally very different from bipolar interneurons."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "qualitative laminar enrichment differences",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-11e0bb0a904f"
  ],
  "source_span": "CCK+ basket cells that co-express VIP have a small soma and are particularly abundant in supragranular layers of the cortex, whereas CCK+ basket cells lacking VIP are enriched in layers 5 and 6.",
  "study_system": "review of mouse cortex VIP/CCK studies",
  "evidence_refs": [
    {
      "ref": "paper:paper-11e0bb0a904f"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "review of Lim 2018 + He 2016 + Tasic 2017 transcriptomic and morphological studies",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}