Version history

{
  "scope": "Mouse and rat; Neuropixels 2.0 chronic recordings, six labs (two species)",
  "claim_text": "Neuropixels 2.0 probes enable chronic recording from the same mouse visual-cortex neurons for over two months by combining >5,000 sites, ~1 g weight including headstage, and post-hoc motion-stabilization algorithms.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1101/2020.10.27.358291",
    "claim": "Neuropixels 2.0 probes enable chronic recording from the same mouse visual-cortex neurons for over two months by combining >5,000 sites, ~1 g weight including headstage, and post-hoc motion-stabilization algorithms.",
    "cite_key": "Steinmetz2020",
    "evidence": "Quantifies the present-day chronic-recording window achievable with the current generation of dense extracellular probes — a hard constraint cluster_14 must report.",
    "effect_size": ">5,000 sites per probe; two probes + headstage ~1 g; 768 sites recorded simultaneously; >10,000-site recordings during free behavior",
    "text_access": "abstract_only",
    "study_system": "Mouse and rat; Neuropixels 2.0 chronic recordings, six labs (two species)",
    "argument_role": "supporting",
    "replication_status": "replicated",
    "claim_source_sentence": "Improved site density and arrangement combined with new data processing methods enable automatic post-hoc stabilization of data despite brain movements during behavior and across days, allowing recording from the same neurons in the mouse visual cortex for over 2 months.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1101/2024.04.25.591118"
    ],
    "effect_size_source_sentence": "The new probe has over 5,000 sites and is miniaturized such that two probes plus a headstage, recording 768 sites at once, weigh just over 1 g, suitable for implanting chronically in small mammals."
  },
  "section_id": "section_15",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json",
  "effect_size": ">5,000 sites per probe; two probes + headstage ~1 g; 768 sites recorded simultaneously; >10,000-site recordings during free behavior",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits",
  "source_kind": "review_finding",
  "source_path": "evidence/section_15_evidence_package.json",
  "source_refs": [
    "paper:272cb25f-50d5-4895-9bd2-9326ef951a25",
    "paper:paper-2c31ad7d8501"
  ],
  "source_span": "Improved site density and arrangement combined with new data processing methods enable automatic post-hoc stabilization of data despite brain movements during behavior and across days, allowing recording from the same neurons in the mouse visual cortex for over 2 months.",
  "study_system": "Mouse and rat; Neuropixels 2.0 chronic recordings, six labs (two species)",
  "evidence_refs": [
    {
      "ref": "paper:272cb25f-50d5-4895-9bd2-9326ef951a25"
    },
    {
      "ref": "paper:paper-2c31ad7d8501"
    }
  ],
  "section_title": "15. Methodological limits and emerging tools — what current mouse-cortex tools cannot yet measure about E→E recurrence (subthreshold network activity, fast plasticity in vivo, millimetre-scale dynamic connectomes), and what is on the near horizon",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Quantifies the present-day chronic-recording window achievable with the current generation of dense extracellular probes — a hard constraint cluster_14 must report.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}